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Talk:Kratom: Difference between revisions
>3xtr4 Rephrased my warning on kratom interactions |
>3xtr4 Expanding my statement on interactions |
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== Interaction Warning == | == Interaction Warning == | ||
Kratom inhibits multiple CYP450 enzymes such as CYP2D6, CYP3A4, and CYP1A2. This has the potential to lead to clinically significant interactions with prescription medication. | Kratom inhibits multiple CYP450 enzymes such as CYP2D6, CYP3A4, and CYP1A2. This has the potential to lead to clinically significant interactions with prescription medication. Also, "Literature indicates that kratom is sometimes fatally mixed with carisoprodol, modafinil, propylhexedrine, Datura stramonium, fentanyl, diphenhydramine, caffeine, morphine, and/or O-desmethyltramadol (Krypton)[7, 8, 21, 35]." (Warner et al 2015) is stated in "The pharmacology and toxicology of kratom: from traditional herb to drug of abuse". Many of the substances listed here are not mentioned as potentially dangerous to mix with kratom. | ||
== Strains section incorrect. Common misunderstanding in kratom == | == Strains section incorrect. Common misunderstanding in kratom == | ||