2-FA: Difference between revisions

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'''2-Fluoroamphetamine''' (also known as '''2-FA''') is a novel [[effect class::stimulant]] substance of the [[chemical class::amphetamine]] class. It is a structural analog of [[amphetamine]] and is presumed to possess a similar mechanism of action, promoting the release of [[dopamine]] and [[norepinephrine]] in the brain.

2-FA is part of a series of amphetamine analogs that first appeared on the online research chemical market in the 2010s.<ref>Isomeric fluoro-methoxy-phenylalkylamines: a new series of controlled-substance analogues (designer drugs) (PubMed.gov / NCBI) | https://www.ncbi.nlm.nih.gov/pubmed/15639609</ref><ref>Chemical analysis of four capsules containing the controlled substance analogues 4-methylmethcathinone, 2-fluoromethamphetamine, alpha-phthalimidopropiophenone and N-ethylcathinone (PubMed.gov / NCBI) | http://www.ncbi.nlm.nih.gov/pubmed/20074881</ref> These compounds ~~includes~~ [[2-FMA]], [[3-FA]], [[3-FEA]] and [[4-FA]]~~. These compounds~~ are ~~known~~ to produce a range of [[stimulant|stimulating]] and [[euphoria|euphoric]] effects, many of which have been used as [[research chemical]] substitutes for classical street [[stimulants]] and [[entactogens]].{{citation needed}} Of these, 2-FA is considered to be most [[amphetamine]]-like in its [[subjective effects]]. It is commonly compared to the d-isomer of amphetamine (dexedrine).

2-FA is part of a series of amphetamine analogs that first appeared on the online research chemical market in the 2010s.<ref>Isomeric fluoro-methoxy-phenylalkylamines: a new series of controlled-substance analogues (designer drugs) (PubMed.gov / NCBI) | https://www.ncbi.nlm.nih.gov/pubmed/15639609</ref><ref>Chemical analysis of four capsules containing the controlled substance analogues 4-methylmethcathinone, 2-fluoromethamphetamine, alpha-phthalimidopropiophenone and N-ethylcathinone (PubMed.gov / NCBI) | http://www.ncbi.nlm.nih.gov/pubmed/20074881</ref> These compounds include [[2-FMA]], [[3-FA]], [[3-FEA]] and [[4-FA]] and are reported to produce a range of [[stimulant|stimulating]] and [[euphoria|euphoric]] effects, many of which have been used as [[research chemical]] substitutes for classical street [[stimulants]] and [[entactogens]].{{citation needed}} Of these, 2-FA is considered to be most [[amphetamine]]-like in its [[subjective effects]]. It is commonly compared to the d-isomer of amphetamine (dexedrine).

2-FA is commonly taken orally. While capable of being taken via [[insufflation]] or [[vaporized|vaporization]], this has been reported to be highly unpleasant and noxious compared to its parent compound. Despite some users reporting efficacy as an alternative to prescription stimulants for ADHD, little is known about the potential toxicological effects that accompany its long-term use as a substitute for prescribed stimulants.

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 '''2-Fluoroamphetamine''' (also known as '''2-FA''') is a novel [[effect class::stimulant]] substance of the [[chemical class::amphetamine]] class. It is a structural analog of [[amphetamine]] and is presumed to possess a similar mechanism of action, promoting the release of [[dopamine]] and [[norepinephrine]] in the brain.
--FA is part of a series of amphetamine analogs that first appeared on the online research chemical market in the 2010s.<ref>Isomeric fluoro-methoxy-phenylalkylamines: a new series of controlled-substance analogues (designer drugs) (PubMed.gov / NCBI) | https://www.ncbi.nlm.nih.gov/pubmed/15639609</ref><ref>Chemical analysis of four capsules containing the controlled substance analogues 4-methylmethcathinone, 2-fluoromethamphetamine, alpha-phthalimidopropiophenone and N-ethylcathinone (PubMed.gov / NCBI) | http://www.ncbi.nlm.nih.gov/pubmed/20074881</ref>  These compounds includes [[2-FMA]], [[3-FA]], [[3-FEA]] and [[4-FA]]. These compounds are known to produce a range of [[stimulant|stimulating]] and [[euphoria|euphoric]] effects, many of which have been used as [[research chemical]] substitutes for classical street [[stimulants]] and [[entactogens]].{{citation needed}} Of these, 2-FA is considered to be most [[amphetamine]]-like in its [[subjective effects]]. It is commonly compared to the d-isomer of amphetamine (dexedrine).
+-FA is part of a series of amphetamine analogs that first appeared on the online research chemical market in the 2010s.<ref>Isomeric fluoro-methoxy-phenylalkylamines: a new series of controlled-substance analogues (designer drugs) (PubMed.gov / NCBI) | https://www.ncbi.nlm.nih.gov/pubmed/15639609</ref><ref>Chemical analysis of four capsules containing the controlled substance analogues 4-methylmethcathinone, 2-fluoromethamphetamine, alpha-phthalimidopropiophenone and N-ethylcathinone (PubMed.gov / NCBI) | http://www.ncbi.nlm.nih.gov/pubmed/20074881</ref>  These compounds include [[2-FMA]], [[3-FA]], [[3-FEA]] and [[4-FA]] and are reported to produce a range of [[stimulant|stimulating]] and [[euphoria|euphoric]] effects, many of which have been used as [[research chemical]] substitutes for classical street [[stimulants]] and [[entactogens]].{{citation needed}} Of these, 2-FA is considered to be most [[amphetamine]]-like in its [[subjective effects]]. It is commonly compared to the d-isomer of amphetamine (dexedrine).
 -FA is commonly taken orally. While capable of being taken via [[insufflation]] or [[vaporized|vaporization]], this has been reported to be highly unpleasant and noxious compared to its parent compound. Despite some users reporting efficacy as an alternative to prescription stimulants for ADHD, little is known about the potential toxicological effects that accompany its long-term use as a substitute for prescribed stimulants.