Banisteriopsis caapi: Difference between revisions
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{{for|the [[DMT]]/[[MAOI]] plant brew that shares the same name as this plant|ayahuasca}} | |||
{{BotanyBox/Banisteriopsis caapi}} | |||
'''''Banisteriopsis caapi''''', also known as '''ayahuasca''', '''caapi''' or '''yagé''', is a South American liana of the family Malpighiaceae. It is used to prepare [[ayahuasca]], a decoction with a long history of its [[entheogen]]ic use and its status as a "plant teacher" among the indigenous peoples of the Amazon rainforest. | |||
==History and culture== | |||
===Research=== | |||
The alkaloids of ''Banisteriopsis caapi'', the plant source of the Amazonian hallucinogen [[ayahuasca]], stimulate adult neurogenesis ''in vitro''.<ref>https://www.nature.com/articles/s41598-017-05407-9</ref> | |||
==Chemistry== | |||
Banisteriopsis caapi (also known as ayahuasca, caapi or yajé) is a South American jungle vine of the family Malpighiaceae. It contains harmine, harmaline, and tetrahydroharmine in the following proportions: | |||
*'''Harmine:''' 0.31-8.43% | |||
*'''Harmaline:''' 0.03-0.83% | |||
* '''Proanthocyanidins''' (less known MAOIs) | |||
** '''(−)-epicatechin''' | |||
** '''(−)-procyanidins''' | |||
*'''Tetrahydroharmine:''' 0.05-2.94% | |||
==Toxicity and harm potential== | |||
===Dangerous interactions=== | |||
====Cholinergics==== | |||
[[Cholinergic]] substances combined with ''Banisteriopsis caapi'' can cause a [https://en.wikipedia.org/wiki/Cholinergic_crisis cholinergic crisis] because the plant contains acetylcholinesterase inhibitors (AChEIs): | |||
* Harmaline<ref name="Pubmed-19784581">https://www.ncbi.nlm.nih.gov/pubmed/19784581</ref> | |||
* Harmine<ref name="Pubmed-19784581" /> | |||
==See also== | |||
*''[[Peganum harmala]]'' | |||
*[[Beta-Carbolines]] | |||
*[[Psychedelics]] | |||
*[[Tryptamines]] | |||
*[[Phenethylamines]] | |||
==External links== | |||
** [https://en.wikipedia.org/wiki/Banisteriopsis_caapi ''Banisteriopsis caapi'' (Wikipedia)] | |||
** [https://erowid.org/plants/banisteriopsis/banisteriopsis.shtml ''Banisteriopsis caapi'' (Erowid Vault)] | |||
* Harmala alkaloids | |||
** [http://en.wikipedia.org/wiki/Harmala_alkaloid Harmala alkaloids (Wikipedia)] | |||
*** [https://en.wikipedia.org/wiki/Harmaline Harmaline (Wikipedia)] | |||
*** [https://en.wikipedia.org/wiki/Harmine Harmine (Wikipedia)] | |||
*** [https://en.wikipedia.org/wiki/Tetrahydroharmine Tetrahydroharmine (Wikipedia)] | |||
** [https://erowid.org/chemicals/harmala/harmala.shtml Harmala Alkaloids (Erowid Vault)] | |||
** [https://isomerdesign.com/PiHKAL/read.php?domain=tk&id=13 Harmaline (TiHKAL / Isomer Design)] | |||
** [https://isomerdesign.com/PiHKAL/read.php?domain=tk&id=14 Harmine (TiHKAL / Isomer Design)] | |||
** [https://isomerdesign.com/PiHKAL/read.php?domain=tk&id=54 Tetrahydroharmine (TiHKAL / Isomer Design)] | |||
==Literature== | |||
* Morales-García, J. A., de la Fuente Revenga, M., Alonso-Gil, S., Rodríguez-Franco, M. I., Feilding, A., Perez-Castillo, A., & Riba, J. (2017). The alkaloids of Banisteriopsis caapi, the plant source of the Amazonian hallucinogen Ayahuasca, stimulate adult neurogenesis in vitro. Scientific Reports, 7(1), 5309. https://doi.org/10.1038/s41598-017-05407-9 | |||
==References== | |||
<references/> | |||
[[Category:Acetylcholinesterase inhibitor]] | |||
[[Category:beta-Carboline]] | |||
[[Category:Entheogen]] | |||
[[Category:MAOI]] | |||
[[Category:Neurogenesis inducer]] | |||
[[Category:Psychoactive substance]] |