3-MeO-PCP: Difference between revisions

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3-MeO-PCP was first synthesized in 1979 in an investigation of [[phencyclidine]] (PCP) derivatives. However, its activity in humans was not described until 1999 when a chemist using the pseudonym John Q. Beagle reported qualitative similarities to [[PCP]] along with comparable potency.<ref name="PCP2MXE">Morris, H., & Wallach, J. (2014). From PCP to MXE: A comprehensive review of the non-medical use of dissociative drugs. Drug Testing and Analysis, 6(7–8), 614–632. https://doi.org/10.1002/dta.1620</ref> In 2009, it began to be discussed on online forums such as bluelight.ru and was made available for sale on the [[research chemicals]] market.<ref>Morris, H., & Wallach, J. (2014). From PCP to MXE: A comprehensive review of the non-medical use of dissociative drugs. Drug Testing and Analysis, 6(7–8), 614–632. https://doi.org/10.1002/dta.1620</ref>

Like other ~~arylcyclohexlyamines~~, 3-MeO-PCP induces a state referred to as "[[dissociatives#Subjective effects|dissociative anesthesia]]", although the extent to which this occurs is reported to be highly dose-dependent and variable in its effects. It is commonly taken [[orally]] and [[nasally]], although it may also be [[smoked]] and [[injected]]. It has been noted for its subtle come up and tendency to produce [[Delusions#Delusion of sobriety|delusions of sobriety]], which can lead to [[compulsive redosing]].

Like other arylcyclohexylamines, 3-MeO-PCP induces a state referred to as "[[dissociatives#Subjective effects|dissociative anesthesia]]", although the extent to which this occurs is reported to be highly dose-dependent and variable in its effects. It is commonly taken [[orally]] and [[nasally]], although it may also be [[smoked]] and [[injected]]. It has been noted for its subtle come up and tendency to produce [[Delusions#Delusion of sobriety|delusions of sobriety]], which can lead to [[compulsive redosing]].

Very little data exists for the pharmacology, metabolism, and toxicity of 3-MeO-PCP. Due to its potent hallucinogenic effects and lack of research, it is strongly advised to use use [[harm reduction practices]] if using this substance.

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 -MeO-PCP was first synthesized in 1979 in an investigation of [[phencyclidine]] (PCP) derivatives. However, its activity in humans was not described until 1999 when a chemist using the pseudonym John Q. Beagle reported qualitative similarities to [[PCP]] along with comparable potency.<ref name="PCP2MXE">Morris, H., & Wallach, J. (2014). From PCP to MXE: A comprehensive review of the non-medical use of dissociative drugs. Drug Testing and Analysis, 6(7–8), 614–632. https://doi.org/10.1002/dta.1620</ref> In 2009, it began to be discussed on online forums such as bluelight.ru and was made available for sale on the [[research chemicals]] market.<ref>Morris, H., & Wallach, J. (2014). From PCP to MXE: A comprehensive review of the non-medical use of dissociative drugs. Drug Testing and Analysis, 6(7–8), 614–632. https://doi.org/10.1002/dta.1620</ref>
-Like other arylcyclohexlyamines, 3-MeO-PCP induces a state referred to as "[[dissociatives#Subjective effects|dissociative anesthesia]]", although the extent to which this occurs is reported to be highly dose-dependent and variable in its effects. It is commonly taken [[orally]] and [[nasally]], although it may also be [[smoked]] and [[injected]]. It has been noted for its subtle come up and tendency to produce [[Delusions#Delusion of sobriety|delusions of sobriety]], which can lead to [[compulsive redosing]].
+Like other arylcyclohexylamines, 3-MeO-PCP induces a state referred to as "[[dissociatives#Subjective effects|dissociative anesthesia]]", although the extent to which this occurs is reported to be highly dose-dependent and variable in its effects. It is commonly taken [[orally]] and [[nasally]], although it may also be [[smoked]] and [[injected]]. It has been noted for its subtle come up and tendency to produce [[Delusions#Delusion of sobriety|delusions of sobriety]], which can lead to [[compulsive redosing]].
 Very little data exists for the pharmacology, metabolism, and toxicity of 3-MeO-PCP. Due to its potent hallucinogenic effects and lack of research, it is strongly advised to use use [[harm reduction practices]] if using this substance.