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2-FMA: Difference between revisions
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{{SubstanceBox/2-FMA}} | {{SubstanceBox/2-FMA}} | ||
'''2-Fluoromethamphetamine''' ('''2-FMA''') is a novel [[psychoactive class::stimulant]] substance of the [[chemical class::amphetamine]] class. | '''2-Fluoromethamphetamine''' (also known as '''2-FMA''') is a novel [[psychoactive class::stimulant]] substance of the [[chemical class::amphetamine]] class. It is a structural analog of [[methamphetamine]] and is related to [[2-FA]], [[3-FA]], and [[4-FMA]]. 2-FMA produces its stimulant effects through action at [[dopamine]] and [[norepinephrine]] receptors in the brain. | ||
2-FMA | 2-FMA first appeared for sale on the online [[research chemical]] market in the mid-2010s.{{citation needed}} It appeared alongside other fluorinated amphetamines like [[2-FA]] and [[4-FA]]. It appears to be unknown in the clinical and research literature. | ||
[[Subjective effects]] include [[stimulation]], [[focus enhancement]], [[motivation enhancement]], [[increased libido]], [[appetite suppression]], and [[euphoria]]. It is commonly taken either orally or via insufflation and is reported to be highly unpleasant to vaporize. 2-FMA is commonly compared to [[lisdexamfetamine]] (Vyvanse) in its duration, potency and efficacy as a study or productivity aid. A substantial increase in adverse effects like [[increased blood pressure|high blood pressure]] and [[increased heart rate]] are often reported for dosages above the heavy dosage range. | |||
Very little data exists about the pharmacological properties, metabolism, and toxicity of 2-FMA. It is strongly advised to use [[harm reduction practices]] if using this substance. | |||
==Chemistry== | ==Chemistry== | ||
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==Subjective effects== | ==Subjective effects== | ||
In comparison to other substituted amphetamines, 2-FMA is reported to be relatively free of side effects such as [[nausea]], [[high blood pressure]], [[anxiety]] and an uncomfortable [[offset]] ("comedown"). It is considered to be a functional stimulant for performing general productivity tasks in a manner similar to [[amphetamine]] or [[lisdexamfetamine]] (Vyvanse). However, at higher doses, it typically loses its productivity and focus-enhancing effects and begins to take on a recreational character due to the distracting euphoria that it can produce. Majority of users report through anecdotal reports that this has a ceiling effect with high dose (Heavy+) ranges where many report of the uncomfortable effects from stimulants when passing or entering the strong-heavy dose range. | In comparison to other substituted amphetamines, 2-FMA is reported to be relatively free of side effects such as [[nausea]], [[high blood pressure]], [[anxiety]] and an uncomfortable [[offset]] ("comedown"). It is considered to be a functional stimulant for performing general productivity tasks in a manner similar to [[amphetamine]] or [[lisdexamfetamine]] (Vyvanse). However, at higher doses, it typically loses its productivity and focus-enhancing effects and begins to take on a recreational character due to the distracting euphoria that it can produce. Majority of users report through anecdotal reports that this has a ceiling effect with high dose (Heavy+) ranges where many report of the uncomfortable effects from stimulants when passing or entering the strong-heavy dose range. | ||
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==Toxicity and harm potential== | ==Toxicity and harm potential== | ||
{{toxicity}} | |||
{{Further|Research chemicals#Toxicity and harm potential}} | {{Further|Research chemicals#Toxicity and harm potential}} | ||
The toxicity and long-term health effects of recreational 2-FMA use do not seem to have been studied in any scientific context and the [[Toxicity::exact toxic dosage is unknown]]. This is because 2-FMA has a very limited history of human usage. | The toxicity and long-term health effects of recreational 2-FMA use do not seem to have been studied in any scientific context and the [[Toxicity::exact toxic dosage is unknown]]. This is because 2-FMA has a very limited history of human usage. | ||
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It is strongly recommended that one use [[responsible drug use|harm reduction practices]] when using this substance. | It is strongly recommended that one use [[responsible drug use|harm reduction practices]] when using this substance. | ||
=== | ===Dependence and abuse potential=== | ||
As with other [[stimulant]]s, the chronic use of 2-FMA can be considered [[Addiction potential::moderately addictive with a high potential for abuse]] and is capable of causing psychological dependence among certain users. When addiction has developed, cravings and [[withdrawal effects]] may occur if a person suddenly stops their usage. | As with other [[stimulant]]s, the chronic use of 2-FMA can be considered [[Addiction potential::moderately addictive with a high potential for abuse]] and is capable of causing psychological dependence among certain users. When addiction has developed, cravings and [[withdrawal effects]] may occur if a person suddenly stops their usage. | ||