Piracetam: Difference between revisions

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==Chemistry==

Piracetam, or 2-oxo-1-pyrrolidine-acetamide, is a synthetic compound of the [[racetam]] family. Racetams share a pyrrolidine nucleus, a five member nitrogenous ring with a ketone bonded oxygen at R<sub>2</sub>.<ref>Piracetam and piracetam-like drugs: from basic science to novel clinical applications to CNS disorders. | http://www.ncbi.nlm.nih.gov/pubmed/20166767</ref> This 2-pyrrolidone ring is bound to the terminal carbon of an acetamide group, an ethyl amide chain with a ketone bond (C=O) at the alpha carbon.

Piracetam, or 2-oxo-1-pyrrolidine-acetamide, is a synthetic compound of the [[racetam]] family. Racetams share a [[pyrrolidine]] nucleus, a five member nitrogenous ring with a ketone bonded oxygen at R<sub>2</sub>.<ref>Piracetam and piracetam-like drugs: from basic science to novel clinical applications to CNS disorders. | http://www.ncbi.nlm.nih.gov/pubmed/20166767</ref> This 2-pyrrolidone ring is bound to the terminal carbon of an acetamide group, an ethyl amide chain with a ketone bond (C=O) at the alpha carbon.

Piracetam shares structural similarity to the neurotransmitter [[GABA]], its pyrrolidine core is the cyclic counterpart of [[GABA]] and could theoretically be converted into an acetamide chain through a hydrolysis reaction into [[GABA]].

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 ==Chemistry==
-Piracetam, or 2-oxo-1-pyrrolidine-acetamide, is a synthetic compound of the [[racetam]] family. Racetams share a pyrrolidine nucleus, a five member nitrogenous ring with a ketone bonded oxygen at R<sub>2</sub>.<ref>Piracetam and piracetam-like drugs: from basic science to novel clinical applications to CNS disorders. | http://www.ncbi.nlm.nih.gov/pubmed/20166767</ref> This 2-pyrrolidone ring is bound to the terminal carbon of an acetamide group, an ethyl amide chain with a ketone bond (C=O) at the alpha carbon.
+Piracetam, or 2-oxo-1-pyrrolidine-acetamide, is a synthetic compound of the [[racetam]] family. Racetams share a [[pyrrolidine]] nucleus, a five member nitrogenous ring with a ketone bonded oxygen at R<sub>2</sub>.<ref>Piracetam and piracetam-like drugs: from basic science to novel clinical applications to CNS disorders. | http://www.ncbi.nlm.nih.gov/pubmed/20166767</ref> This 2-pyrrolidone ring is bound to the terminal carbon of an acetamide group, an ethyl amide chain with a ketone bond (C=O) at the alpha carbon.
 Piracetam shares structural similarity to the neurotransmitter [[GABA]], its pyrrolidine core is the cyclic counterpart of [[GABA]] and could theoretically be converted into an acetamide chain through a hydrolysis reaction into [[GABA]].