Talk:Lithium: Difference between revisions

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==Pharmacology==

Lithium carbonate is used to treat mania, the elevated phase of bipolar disorder. Lithium ions interfere with ion transport processes (see “sodium pump”) that relay and amplify messages carried to the cells of the brain. Mania is associated with irregular increases in protein kinase C (PKC) activity within the brain. Lithium carbonate and sodium valproate, another drug traditionally used to treat the disorder, act in the brain by inhibiting PKC's activity and help to produce other compounds that also inhibit the PKC. Lithium carbonate's mood-controlling properties are not fully understood.

Lithium has a complex pharmacology.

~~Adverse reactions~~

~~Taking lithium salts~~ has risks and side effects. Extended use of lithium to treat various mental disorders has been known to lead to acquired nephrogenic diabetes insipidus. Lithium intoxication can affect the central nervous system and renal system and can be lethal.

==Subjective effects==

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*'''[[Psychedelics]]''' - This combination has been reported by users to cause seizures and psychotic breaks, notably with [[LSD]]. At least one death has been reported to be triggered by the combination of LSD and lithium.<ref>http://www.erowid.org/chemicals/lsd/lsd_health3.shtml</ref>

*'''[[Psychedelics]]''' - This combination has been reported by many users to cause seizures and psychotic breaks, notably with [[LSD]]. At least one death has been reported to be triggered by the combination of LSD and lithium.<ref>http://www.erowid.org/chemicals/lsd/lsd_health3.shtml</ref>

==Legal status==

@@ Line 16: / Line 16: @@
 ==Pharmacology==
 {{pharmacology}}
-Lithium carbonate is used to treat mania, the elevated phase of bipolar disorder. Lithium ions interfere with ion transport processes (see “sodium pump”) that relay and amplify messages carried to the cells of the brain. Mania is associated with irregular increases in protein kinase C (PKC) activity within the brain. Lithium carbonate and sodium valproate, another drug traditionally used to treat the disorder, act in the brain by inhibiting PKC's activity and help to produce other compounds that also inhibit the PKC. Lithium carbonate's mood-controlling properties are not fully understood.
+Lithium has a complex pharmacology.
-Adverse reactions
-Taking lithium salts has risks and side effects. Extended use of lithium to treat various mental disorders has been known to lead to acquired nephrogenic diabetes insipidus. Lithium intoxication can affect the central nervous system and renal system and can be lethal.
 ==Subjective effects==
 {{EffectStub}}
@@ Line 39: / Line 36: @@
 {{DangerousInteractions}}
 {{DangerousInteractions/Intro}}
-*'''[[Psychedelics]]''' - This combination has been reported by users to cause seizures and psychotic breaks, notably with [[LSD]]. At least one death has been reported to be triggered by the combination of LSD and lithium.<ref>http://www.erowid.org/chemicals/lsd/lsd_health3.shtml</ref>
+*'''[[Psychedelics]]''' - This combination has been reported by many users to cause seizures and psychotic breaks, notably with [[LSD]]. At least one death has been reported to be triggered by the combination of LSD and lithium.<ref>http://www.erowid.org/chemicals/lsd/lsd_health3.shtml</ref>
 ==Legal status==