Talk:BOD: Difference between revisions

>Eve DJMDEA
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>Eve DJMDEA
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'''4-methyl-2,5,beta-trimethoxyphenethylamine''' (also known as '''BOD''' ) is a lesser-known [[psychoactive class::psychedelic]] and [[psychoactive class::entactogen]] substance of the [[chemical class::phenethylamine]] class. BOD is a member of the [[BOx]] family of compounds which are relatively unknown, and have only recently found sales in the research chemical community.
BOD was first synthesized and tested  by [[Alexander Shulgin]].<ref name="BOD">Shulgin, Alexander (1991). PiHKAL: A Chemical Love Story. Berkeley, CA: Transform Press. pp. 53–56.</ref> It gained little popularity and even by 2019 it is still relatively unknown. In 1991, the synthesis and pharmacology of BOD was published in Shulgin's book ''[[PiHKAL]]'' ("Phenethylamines I Have Known And Loved").<ref name="PiHKAL">http://www.erowid.org/library/books_online/pihkal/pihkal.shtml</ref>.
From the few reports of it, BOD seems to be very much like the [[DOx]] family compounds in terms of it being dose sensitive, long lasting, intense, and very stimulating albeit much less potent. However, its chemical structure is related to compounds of the trimethoxyamphetamine class, and it may share a similar pharmacological profile to both.


For tips on how to properly format a substance article, please refer to this document: [[Content Style Guide - Substance]]
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==Chemistry==
==Chemistry==
{{chemistry}}
BOD, or 4-methyl-2,5,beta-trimethoxyphenethylamine is a molecule of the [[substituted phenethylamine]] class. BOD was the first BOx compound shulgin studied and it is the beta-methoxy analog of [[2cd]]. Shulgin only looked into 4 [[BOx]] compounds of which only [[BOB]] and [[BOD]] were found to have psychedelic and enacteogenic effects.
==Pharmacology==
==Pharmacology==
{{pharmacology}}
{{pharmacology}}


==Subjective effects==
==Subjective effects==
{{EffectStub}}
Most users describe BOD as being clearheaded and lucid at lower doses, in ways reminescent of most 2cx's. At higher doses however the expierence can become highly intense and in some cases produces unique effects which are not found in other [[psychoactive class::psychedelics]].
{{Preamble/SubjectiveEffects}}
{{Preamble/SubjectiveEffects}}
{{effects/base
{{effects/base


|{{effects/physical|
|{{effects/physical|
If applicable, a brief paragraph summary of the substance's physical effects may be included here.  
The body load on BOD is relatively light, it is more comparable to [[LSD]] than to [[DOx]] compounds.


You may select physical effects to add below [[Subjective effect index#Physical effects|here]].
You may select physical effects to add below [[Subjective effect index#Physical effects|here]].


*'''[[Effect::Physical effect]]'''  
*'''[[Effect::Stimulation]]'''
*'''[[Effect::Physical effect2]]'''
The stimulation produced by BOD is strong and noticable and encourages one to move around and do physical activities while still being not forced so that one can simply sit down and watch something and not feel the urge to move, it is very much like substances such as [[2C-B]], or [[LSD]].
*'''[[Effect::Physical effect3]]'''
*'''[[Effect::Spontaneous Physical Sensations]]'''
The body high of BOD is often described as being dose sensitive, with medium to higher doses producing strong  overwhelming sensations of tingling and pleasurable feelings. At the highest level the sensations can be subjectively felt as though one can feel every single nerve ending on their body and the tingling becomes a feeling of the minute chemical reactions between outside particles and the individual cells.
*'''[[Effect::Increased Bodily Temperature]]'''
BOD increases ones body temperature in a way unlike most psychedelics and as an effect of this there is very strong perspiration. However anecdotally the sensation while uncomfortable can be easily stopped by applying antiperspirants. As well, being outside or in a place with air circulation makes the sensation barely noticable.
*'''[[Effect::Appetite Enhancement]]'''
In contrast to stimulating psychedelics such as [[LSD]], [[DOM]] or [[2C-B]] BOD increases one's appetite in a way that while not forced, makes it very easy to be eating something especially if one is sitting down or relaxing.


}}
}}
{{effects/visual|
{{effects/visual|
If applicable, a brief paragraph summary of the substance's visual effects may be included here.  
The visual effects of BOD are very strong and reproducible in a way that is more like [[2C-B]], or other strongly visual psychedelics. This effect becomes quite pronounced at higher doses as the cognitive effects and physical effects seem to combine with the visual producing a state that is unlike most commonly used psychedelics.


You may select visual effects to add below [[Subjective effect index#Visual effects|here]].
You may select visual effects to add below [[Subjective effect index#Visual effects|here]].


====Enhancements====
====Enhancements====
*'''[[Effect::Visual acuity effect1]]'''
*'''[[Effect::Acuity Enhancement]]'''
*'''[[Effect::Color Enhancement]]'''


====Distortions====
====Distortions====
*'''[[Effect::Visual distortion effect1]]'''
*'''[[Effect::Depth Perception Disorders]]'''
*'''[[Effect::Drifting]]'''
*'''[[Effect::Color Shifting]]'''
*'''[[Effect::Brightness Alteration]]'''
*'''[[Effect::Tracers]]'''


====[[Effect::Geometry]]====
====[[Effect::Geometry]]====
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|{{effects/cognitive|
|{{effects/cognitive|
The cognitive effects of BOD are very clearheaded and lucid while also allowing for deeper cognitive thoughts in a way that is more alike to substances like 2cb,DOM, and other phenethylamines, while also at higher doses becoming very deep and seemingly profound in a way reminescent of deeper psychedelics.
The Headspace of BOD can be described as analytical, lucid, with the capability at higher doses of becoming very intense. Anecdotally reports have said that higher doses produce a state of confusion that while still euphoric is very intense while lower doses do not seem to induce those effects.
 
You may select from a list of cognitive effects to add below [[Subjective effect index#Cognitive effects|here]].
You may select from a list of cognitive effects to add below [[Subjective effect index#Cognitive effects|here]].


*'''[[Effect::Cognitive effect1]]'''  
*'''[[Effect::Empathy, Affection, and socialability Enhancement]]'''  
*'''[[Effect::Cognitive effect2]]'''  
The entactogenic effects of BOD are much more pronounced than most psychdelics, and while not as strong as [[MDMA]], are strong enough to produce some theraputic effects for certain people.
*'''[[Effect::Cognitive effect3]]'''  
*'''[[Effect::Increased Sense of Humor ]]'''  
This is one of the more promenint effects of BOD, and is unlike most [[psychoactive class::psychedelics]]. It is very similar to the effects of cannabinoids such as [[cannabis]]
*'''[[Effect::Emotion Enhancement]]'''  
While BOD produces a mostly euphoric state, like most psychedelics the high can change quite rapidly from euphoric to dysphoric merely due to emotional changes. This is an intense state which is less controllable than in other clear headed psychedelics and can feel quite strange and scary if one is unprepared.


}}
}}
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You may select from a list of auditory effects to add below [[Subjective effect index#Auditory effects|here]].
You may select from a list of auditory effects to add below [[Subjective effect index#Auditory effects|here]].


*'''[[Effect::Auditory effect1]]'''
*'''[[Effect::Auditory Distortion]]'''
*'''[[Effect::Auditory effect2]]'''
This effect occurs mainly at higher doses and is typically a sense of hearing words in languages you understand as being foreign or incomprehensible.
*'''[[Effect::Auditory Hallucinations]]'''
*'''[[Effect::Auditory Enhancment]]'''


}}
}}
{{effects/multisensory|
{{effects/multisensory|
The synesthesic effects of BOD, are an intense and overwhelming expierence especially at high doses. At the highest ranges it can feel as though one is feeling every single neuron in their head interconnected in a way which emphasizes the body high.
The synaesthesic effects of BOD, are an intense and more reproducible effect than in substances like [[LSD]]


You may select from a list of multisensory effects to add below [[Subjective effect index#Multisensory effects|here]].
You may select from a list of multisensory effects to add below [[Subjective effect index#Multisensory effects|here]].


*'''[[Effect::Multisensory effect1]]'''  
*'''[[Effect::Synaesthesia]]'''  
*'''[[Effect::Multisensory effect2]]'''
In comparison to [[LSD]] the synaesthesia produce by BOD is much more intense and can be overwhelming. At its highest level it becomes a state much more profound than in most other synaesthesic compounds.
 
}}
{{effects/transpersonal|
{{effects/transpersonal|
If applicable, a brief paragraph summary of the substance's transpersonal effects may be included here.  
These effects are likely very rare, and the only person who as of 2019 has reported it took a much higher dose than most people would be taking. Caution is advised.


You may select from a list of transpersonal effects to add below [[Subjective effect index#Transpersonal effects|here]].
You may select from a list of transpersonal effects to add below [[Subjective effect index#Transpersonal effects|here]].


*'''[[Effect::Transpersonal effect1]]'''
*'''[[Effect::Unity and Interconnectedness]]'''
*'''[[Effect::Transpersonal effect2]]'''
BOD produces a unique state of unity which is subjectively described as a state of realizing the unity of the organisms which make up oneself. Rather than a unity with beings outside of the self there is a strong sense of being in total interconnection through the senses and through all the cells in ones body. This expeirence is rather profound and is almost always combined with synaesthesia, and level 8A geometry.
*'''[[Effect::Existential Self-Realization]]'''
BOD produces self realization in a way that can be considered more intense than substances such as [[LSD]]. These realizations can sometimes feel much more intensee than one might normally want from a trip and as such care must be taken to always have a person one can talk to due to the intensity of the realizations.


}}
}}
}}
}}
===Experience reports===
===Experience reports===
There are currently {{#ask:[[Category:SUBSTANCE]][[Category:Experience]] | format=count}} experience reports which describe the effects of this substance in our [[experience index]].
There are currently no experience reports which describe the effects of this substance in our [[experience index]].
{{#ask: [[Category:SUBSTANCE]][[Category:Experience]]|format=ul|Columns=1}}
{{#ask: [[Category:SUBSTANCE]][[Category:Experience]]|format=ul|Columns=1}}
Additional experience reports can be found here:
Additional experience reports can be found here:
* [https://www.erowid.org/experiences/subs/exp_SUBSTANCE.shtml Erowid Experience Vaults: SUBSTANCE] <!-- Check the link to see if it exists -->
* [https://www.erowid.org/experiences/subs/exp_BOD.shtml Erowid Experience Vaults: BOD] <!-- Check the link to see if it exists -->


==Toxicity and harm potential==
==Toxicity and harm potential==
{{BOD has had such a limited history of us that while anecdotal reports list doses as high as 60mg with little dangerous effects, without any pharmacological information it is safest to practice harm reduction with this substance.}}
{BOD has had such a limited history of us that as of 2019 while certain individuals are able to use as high as 70mg, and given the reduced potency compared to other long lasting [[psychoactive class::psychedelic]] it is most likely BOD has a toxicity profile comparable to the [[2Cx]] compounds. However given its strong dose response curve, the little information about the substance, and the long come up. It is strongly recommended that one use [[responsible use|harm reduction practices]] when using this substance.
It is strongly recommended that one use [[responsible use|harm reduction practices]] when using this substance.
===Lethal dosage===
===Lethal dosage===
The highest dose consumed of BOD that has been reported so far is around 70mg. BOD has very little likihood of being a full agonist of 5-HT2A but that does not mean it is a purely safe psychedelic. While most dose ranges display common doses at 20-30mg, due to the substances response curve and its slow come up, the dose information currently available may not be correct, as other subtances Shulgin studied he found inactive were actually active at much higher doses.
===Tolerance and addiction potential===
===Tolerance and addiction potential===
===Dangerous interactions===
===Dangerous interactions===
{{DangerousInteractions}}
{{DangerousInteractions}}
{{DangerousInteractions/Intro}}
{{DangerousInteractions/Intro}}
 
*'''[[Tramadol]]''' - Tramadol lowers the seizure threshold<ref>Talaie, H., Panahandeh, R., Fayaznouri, M. R., Asadi, Z., & Abdollahi, M. (2009). Dose-independent occurrence of seizure with tramadol. Journal of medical toxicology, 5(2), 63-67. doi:10.1007/BF03161089</ref> and [[psychedelics]] may act as triggers for seizures, particularly in those who are predisposed to them.{{citation needed}}
*'''[[Stimulants]]''' - Stimulants affect many parts of the brain. Combined with psychedelics, stimulation can turn into uncontrollable [[anxiety]], [[Panic attacks|panic]], [[thought loops]] and [[paranoia]]. This interaction may cause elevated risk of psychosis.{{citation needed}}
*'''[https://en.wikipedia.org/wiki/Lithium_(medication) Lithium]''' - Lithium is often used as treatment for bipolar disorder. It may possibly cause elevated risk of seizures and psychosis due to its [[Glutamate|glutaminergic]] and [[GABA|GABAergic]] effects.{{citation needed}}
*'''[[Serotonin Syndrome]]''' - Due to BOD's obscurity and its strong entactogenic effects, it is avisable for users to be very wary of combining serotonin releasing agents or ssris. Anecdotally a user was able to consume [[DXM]] during the comedown and was fine, but this does not mean that it is a safe combination and until further studies have been made, it is highly advisable to take lower doses of [[MDMA]] or other entactogens than one would with psychedelics such as [[LSD]]
==Legal status==
==Legal status==
{{BOD is currently unscheduled in the United States, however it due to its chemical similarity to 2c-d it may be charged under the federal analog act if being purchased for human consumption.}}
{{BOD is currently unscheduled in the United States, however it due to its chemical similarity to 2c-d it may be charged under the federal analog act if being purchased for human consumption.}}
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