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Gabapentin: Difference between revisions
>AlienSexFiend →Subjective effects: Added acronym for closed eye visuals. |
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==Subjective effects== | ==Subjective effects== | ||
The decreasing bioavailability of gabapentin can be lessened by taking lower doses more often instead of higher doses less frequently. As a general rule, using any more than 250- | The decreasing bioavailability of gabapentin can be lessened by taking lower doses more often instead of higher doses less frequently. As a general rule, using any more than 250-300 mg of gabapentin every 30-45 minutes will result in wasting a significant portion of the total dose of gabapentin, although this number varies depending on the individual. Alkaline environments inhibit absorption of gabapentin, so lowering the pH of one's stomach using acidic substances (such as soft drinks) will boost bioavailability as well. It is generally not recommended to take antacids 2 hours before or after taking gabapentin, because although not dangerous, it will severely lower the total absorption of gabapentin.<ref><nowiki>https://www.uofmhealth.org/health-library/d03182a1</nowiki></ref> | ||
{{Preamble/SubjectiveEffects}} | {{Preamble/SubjectiveEffects}} | ||
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|{{effects/physical| | |{{effects/physical| | ||
*'''[[Effect::Sedation]]''' - | *'''[[Effect::Sedation]]''' - Gabapentin is typically mildly sedating and can produce a lethargic state. At higher doses it may lead to a moderately sedated state. | ||
*'''[[Effect::Appetite enhancement]]''' - | *'''[[Effect::Appetite enhancement]]''' - Appetite enhancement is not particularly prominent, but is sometimes reported. It can have a synergistic effect when combined with [[cannabis]]. | ||
*'''[[Effect::Muscle relaxation]]''' - | *'''[[Effect::Muscle relaxation]]''' - Muscle relaxation is present on gabapentin, although not to the extent of [[benzodiazepines]], [[barbiturates]], or [[GHB]]. | ||
*'''[[Effect::Physical euphoria]]''' | *'''[[Effect::Physical euphoria]]''' - Gabapentin is capable of producing weak to moderate states of physical euphoria in some users. However, it is very inconsistent compared to other depressants (e.g. [[benzodiazepines]], [[opioids]], and [[GHB]]) and tolerance builds rapidly. As a result, it is considered to be a poor euphoriant. | ||
*'''[[Effect::Decreased libido]]''' - Many users note a marked decrease in their sex drive when taking gabapentin. This can happen when it is taken both recreationally or | *'''[[Effect::Decreased libido]]''' - Many users note a marked decrease in their sex drive when taking gabapentin. This can happen when it is taken both recreationally or as prescribed. | ||
*'''[[Effect::Perception of bodily lightness]]''' - | *'''[[Effect::Perception of bodily lightness]]''' - Some users report feeling lighter at very high doses. | ||
*'''[[Effect::Dizziness]]''' - | *'''[[Effect::Dizziness]]''' - Dizziness is prevalent at higher doses, although many users report that it is not necessarily distressing. However, users should be careful not to slip and fall when walking down slopes or stairs. | ||
*'''[[Effect::Seizure suppression]]''' - Gabapentin is commonly used as an anticonvulsant. It is often combined with other anticonvulsants when used to treat epilepsy and other seizure disorders. | *'''[[Effect::Seizure suppression]]'''{{citation needed}} - Gabapentin is commonly used as an anticonvulsant. It is often combined with other anticonvulsants when used to treat epilepsy and other seizure disorders. | ||
*'''[[Effect::Pain relief]]''' - Gabapentin is used to control pain, particularly fibromyalgic/neuropathic pain (nerve pain) and [[restless leg syndrome]]. It is generally considered to be not very effective for the management of acute pain, such as [[opiates]]. | *'''[[Effect::Pain relief]]''' - Gabapentin is used to control pain, particularly fibromyalgic/neuropathic pain (nerve pain) and [[restless leg syndrome]].{{citation needed}} It is generally considered to be not very effective for the management of acute pain, such as [[opiates]]. | ||
*'''[[Effect::Muscle twitching]]''' | *'''[[Effect::Muscle twitching]]''' | ||
*'''[[Effect::Motor control loss]]''' | *'''[[Effect::Motor control loss]]''' | ||
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{{effects/visual| | {{effects/visual| | ||
====Hallucinatory states==== | ====Hallucinatory states==== | ||
*'''[[Effect::Internal hallucination]]''' - At higher doses, some users report mild to strong closed eye visuals | *'''[[Effect::Internal hallucination]]''' - At higher doses, some users report mild to strong closed eye visuals (CEVs). These can include, but are not limited to [[psychedelic]]-like [[geometry]] and landscapes. It has been noted that smoking [[cannabis]] greatly potentiates these effects. | ||
====Disconnective effects==== | ====Disconnective effects==== | ||
*'''[[Effect::Visual disconnection]]''' - This effect is generally quite mild and appears inconsistently at very high doses. It results in feeling as if one's sense of vision is distant or vague and being viewed through a screen or window. However, it is not capable of higher levels of visual disconnection that produce [[holes, spaces and voids]] or [[Visual_disconnection#Structures|hallucinatory structures]] in the same way that traditional [[dissociatives]] can. | *'''[[Effect::Visual disconnection]]''' - This effect is generally quite mild and appears inconsistently at very high doses. It results in feeling as if one's sense of vision is distant or vague and being viewed through a screen or window. However, it is not capable of higher levels of visual disconnection that produce [[holes, spaces and voids]] or [[Visual_disconnection#Structures|hallucinatory structures]] in the same way that traditional [[dissociatives]] can. | ||