Talk:Trazodone: Difference between revisions

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'''Trazodone''', first sold as '''Oleptro''', is an antidepresant of the [[Serotonin#Antagonists|serotonin antagonist]] and [[reuptake inhibitor]] (SARI) class, approved as a prescription medicine for major depressive disorder in adults. Trazodone ~~has~~ [[mCPP|''meta''-Chlorophenylpiperazine]] or [[mCPP|"chlorophenylpiperazine"]] as an active metabolite ~~that~~ contributes to trazodone's pharmacology. <ref> 1-m-Chlorophenylpiperazine is an active metabolite common to the psychotropic drugs trazodone, etoperidone and mepiprazole | http://onlinelibrary.wiley.com/doi/10.1111/j.2042-7158.1982.tb04701.x/abstract;jsessionid=9006CB66248FC2F30E99D5AEAB847661.f04t01</ref>

'''Trazodone''', first sold as '''Oleptro''', is an antidepresant of the [[Serotonin#Antagonists|serotonin antagonist]] and [[reuptake inhibitor]] (SARI) class, approved as a prescription medicine for major depressive disorder in adults. Trazodone produces [[mCPP|''meta''-Chlorophenylpiperazine]] ([[mCPP|"chlorophenylpiperazine"]]) as an active metabolite; it contributes to trazodone's pharmacology. <ref> 1-m-Chlorophenylpiperazine is an active metabolite common to the psychotropic drugs trazodone, etoperidone and mepiprazole | http://onlinelibrary.wiley.com/doi/10.1111/j.2042-7158.1982.tb04701.x/abstract;jsessionid=9006CB66248FC2F30E99D5AEAB847661.f04t01</ref>

[[File:Trazodone (mCPP moiety labelled).svg|300px|thumbnail|right|Trazodone. Notice the [[mCPP]] moiety.]]

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 {{SubstanceBox/Trazodone}}
-'''Trazodone''', first sold as '''Oleptro''', is an antidepresant of the [[Serotonin#Antagonists|serotonin antagonist]] and [[reuptake inhibitor]] (SARI) class, approved as a prescription medicine for major depressive disorder in adults. Trazodone has [[mCPP|''meta''-Chlorophenylpiperazine]] or  [[mCPP|"chlorophenylpiperazine"]] as an active metabolite that contributes to trazodone's pharmacology. <ref> 1-m-Chlorophenylpiperazine is an active metabolite common to the psychotropic drugs trazodone, etoperidone and mepiprazole | http://onlinelibrary.wiley.com/doi/10.1111/j.2042-7158.1982.tb04701.x/abstract;jsessionid=9006CB66248FC2F30E99D5AEAB847661.f04t01</ref>
+'''Trazodone''', first sold as '''Oleptro''', is an antidepresant of the [[Serotonin#Antagonists|serotonin antagonist]] and [[reuptake inhibitor]] (SARI) class, approved as a prescription medicine for major depressive disorder in adults. Trazodone produces [[mCPP|''meta''-Chlorophenylpiperazine]] ([[mCPP|"chlorophenylpiperazine"]]) as an active metabolite; it contributes to trazodone's pharmacology. <ref> 1-m-Chlorophenylpiperazine is an active metabolite common to the psychotropic drugs trazodone, etoperidone and mepiprazole | http://onlinelibrary.wiley.com/doi/10.1111/j.2042-7158.1982.tb04701.x/abstract;jsessionid=9006CB66248FC2F30E99D5AEAB847661.f04t01</ref>
 [[File:Trazodone (mCPP moiety labelled).svg|300px|thumbnail|right|Trazodone. Notice the [[mCPP]] moiety.]]