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Releasing agent: Difference between revisions
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A '''releasing agent''', or simply releaser, is a drug that induces the release of a [[neurotransmitter]] from the presynaptic [[neuron]] into the synapse, leading to a rise in the extracellular concentrations of the neurotransmitter, therefore resulting in increased neurotransmission. Many drugs use neurotransmitter release to exert their psychological and physiological effects, namely the [[amphetamines]] and related compounds. Virtually all currently known releasing agents affect the monoamine neurotransmitters [[serotonin]], [[noradrenaline]], and/or [[dopamine]], and as such, they are often referred to more formally as monoamine releasing agents (MRAs). MRAs may be selective for a particular neurotransmitter or non-selective and affect multiple neurotransmitters. | A '''releasing agent''', or simply releaser, is a drug that induces the release of a [[neurotransmitter]] from the presynaptic [[neuron]] into the synapse, leading to a rise in the extracellular concentrations of the neurotransmitter, therefore resulting in increased neurotransmission. Many drugs use neurotransmitter release to exert their psychological and physiological effects, namely the [[amphetamines]] and related compounds. Virtually all currently known releasing agents affect the monoamine neurotransmitters [[serotonin]], [[noradrenaline]], and/or [[dopamine]], and as such, they are often referred to more formally as monoamine releasing agents (MRAs). MRAs may be selective for a particular neurotransmitter or non-selective and affect multiple neurotransmitters. | ||