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2C-H: Difference between revisions
>Kenan m Redo addition by natzki with different citation format and different phrasing |
>LockPicker Added legal situation in germany |
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==Pharmacology== | ==Pharmacology== | ||
There is no record of 2C-H trials in humans, as it would likely be destroyed by monoamine oxidase enzymes before causing any significant psychoactive effects.<ref> [[Alexander Shlulgin|Shulgin, Alexander]]; [[Ann Shulgin]] (September 1991). [https://www.erowid.org/library/books_online/pihkal/pihkal023.shtml PiHKAL: A Chemical Love Story.] Berkeley, California: Transform Press. ISBN 0-9630096-0-5. OCLC 25627628.</ref> Very little data exists about the pharmacological properties, metabolism, and toxicity of 2C-H. However, it has been shown to have binding affinity towards [[Serotonin#The_5-HT_system|5-HT2C]] and [[Serotonin#The_5-HT_system|5-HT2A]] [[receptor]]s in rats.<ref>2C-H BioAssay Results (PubChem) | https://pubchem.ncbi.nlm.nih.gov/compound/76632#section=BioAssay-Results</ref> 2C-H has been shown to inhibit MAO-B activity by over 50% in experiments.<ref name="WagmannBrandt2019">{{cite journal|last1=Wagmann|first1=Lea|last2=Brandt|first2=Simon D.|last3=Stratford|first3=Alexander|last4=Maurer|first4=Hans H.|last5=Meyer|first5=Markus R.|title=Interactions of phenethylamine-derived psychoactive substances of the 2C-series with human monoamine oxidases|journal=Drug Testing and Analysis|volume=11|issue=2|year=2019|pages=318–324|issn=19427603|doi=10.1002/dta.2494}}</ref> | There is no record of 2C-H trials in humans, as it would likely be destroyed by monoamine oxidase enzymes before causing any significant psychoactive effects.<ref>[[Alexander Shlulgin|Shulgin, Alexander]]; [[Ann Shulgin]] (September 1991). [https://www.erowid.org/library/books_online/pihkal/pihkal023.shtml PiHKAL: A Chemical Love Story.] Berkeley, California: Transform Press. ISBN 0-9630096-0-5. OCLC 25627628.</ref> Very little data exists about the pharmacological properties, metabolism, and toxicity of 2C-H. However, it has been shown to have binding affinity towards [[Serotonin#The_5-HT_system|5-HT2C]] and [[Serotonin#The_5-HT_system|5-HT2A]] [[receptor]]s in rats.<ref>2C-H BioAssay Results (PubChem) | https://pubchem.ncbi.nlm.nih.gov/compound/76632#section=BioAssay-Results</ref> 2C-H has been shown to inhibit MAO-B activity by over 50% in experiments.<ref name="WagmannBrandt2019">{{cite journal|last1=Wagmann|first1=Lea|last2=Brandt|first2=Simon D.|last3=Stratford|first3=Alexander|last4=Maurer|first4=Hans H.|last5=Meyer|first5=Markus R.|title=Interactions of phenethylamine-derived psychoactive substances of the 2C-series with human monoamine oxidases|journal=Drug Testing and Analysis|volume=11|issue=2|year=2019|pages=318–324|issn=19427603|doi=10.1002/dta.2494}}</ref> | ||
==Subjective effects== | ==Subjective effects== | ||
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*'''Austria:''' 2C-H is illegal to possess, produce and sell under the NPSG (Neue-Psychoaktive-Substanzen-Gesetz Österreich).{{citation needed}} | *'''Austria:''' 2C-H is illegal to possess, produce and sell under the NPSG (Neue-Psychoaktive-Substanzen-Gesetz Österreich).{{citation needed}} | ||
*'''Canada:''' As of October 31st, 2016, 2C-H is a controlled substance (Schedule III) in Canada, and is thus illegal to possess, produce and sell.<ref>http://gazette.gc.ca/rp-pr/p2/2016/2016-05-04/html/sor-dors72-eng.php</ref> | *'''Canada:''' As of October 31st, 2016, 2C-H is a controlled substance (Schedule III) in Canada, and is thus illegal to possess, produce and sell.<ref>http://gazette.gc.ca/rp-pr/p2/2016/2016-05-04/html/sor-dors72-eng.php</ref> | ||
*'''Germany:''' 2C-H is controlled by the NpSG, as it is a derivative of 2-Phenethylamine. Production and sale is illegal. Possession and import, although illegal, is not penalized if intended for self-consumption.<ref>https://www.gesetze-im-internet.de/npsg/anlage.html</ref> | |||
*'''United States:''' As of July 9, 2012, 2C-H is a Schedule I controlled substance in the United States, under the Synthetic Drug Abuse Prevention Act of 2012.<ref>https://www.deadiversion.usdoj.gov/fed_regs/rules/2013/fr0104.htm</ref> | *'''United States:''' As of July 9, 2012, 2C-H is a Schedule I controlled substance in the United States, under the Synthetic Drug Abuse Prevention Act of 2012.<ref>https://www.deadiversion.usdoj.gov/fed_regs/rules/2013/fr0104.htm</ref> | ||
*'''United Kingdom''' - 2C-H is a Class A drug in the United Kingdom as a result of the phenethylamine catch-all clause.<ref>United Kingdom. (1977). Misuse of Drugs Act 1971 (S.I. 1977/1243). London: The Stationery Office Limited. Retrieved July 5, 2017, from http://www.legislation.gov.uk/uksi/1977/1243/made</ref> | *'''United Kingdom''' - 2C-H is a Class A drug in the United Kingdom as a result of the phenethylamine catch-all clause.<ref>United Kingdom. (1977). Misuse of Drugs Act 1971 (S.I. 1977/1243). London: The Stationery Office Limited. Retrieved July 5, 2017, from http://www.legislation.gov.uk/uksi/1977/1243/made</ref> | ||
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==References== | ==References== | ||
<references/> | <references /> | ||
[[Category:Phenethylamine]] | [[Category:Phenethylamine]] | ||
[[Category:Psychoactive substance]] | [[Category:Psychoactive substance]] | ||