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Although many psychoactive substances are safe to use on their own, they can quickly become | Although many psychoactive substances are reasonably safe to use on their own, they can quickly become harmful and even life-threatening when taken with other substances. The following section lists some known dangerous combinations, but it may not include all of them. Furthermore, a combination that seems to be harmless in low doses can still greatly increase the risk of injury or death when the doses are slightly increased. [https://www.google.com/ Independent research] should ''always'' be conducted to ensure that a combination of two or more substances is safe to consume. Some interactions listed have been sourced from [https://combo.tripsit.me Tripsit]. | ||