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5-Hydroxytryptophan: Difference between revisions
>Kenan m Fix several interactions |
>Tracer m [https://www.erowid.org/experiences/subs/exp_Tryptophan_5HTP.shtml Erowid Experience Vaults: 5-HTP] |
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*'''[[Effect::Auditory hallucinations|Hallucinations]]''' - Auditory hallucinations have been reported on 5-HTP, however they are rare and only occur at high dosages. | *'''[[Effect::Auditory hallucinations|Hallucinations]]''' - Auditory hallucinations have been reported on 5-HTP, however they are rare and only occur at high dosages. | ||
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===Experience reports=== | |||
There are currently no anecdotal reports which describe the effects of this compound within our [[experience index]]. Additional experience reports can be found here: | |||
* [https://www.erowid.org/experiences/subs/exp_Tryptophan_5HTP.shtml Erowid Experience Vaults: 5-HTP] | |||
==Toxicity and harm potential== | ==Toxicity and harm potential== | ||
Due to the conversion of 5-HTP into serotonin by the liver, with prolonged use, there may be a significant risk of heart valve disease from serotonin's effect on the heart, which is thought to be due to agonism of the 5-HT<sub>2B</sub> receptors present on it.<ref>https://www.ncbi.nlm.nih.gov/pubmed/15781732 | Long-term serotonin administration induces heart valve disease in rats.</ref><ref>https://www.ncbi.nlm.nih.gov/pubmed/12466135 | Serotonin mechanisms in heart valve disease II: the 5-HT2 receptor and its signaling pathway in aortic valve interstitial cells.</ref> | Due to the conversion of 5-HTP into serotonin by the liver, with prolonged use, there may be a significant risk of heart valve disease from serotonin's effect on the heart, which is thought to be due to agonism of the 5-HT<sub>2B</sub> receptors present on it.<ref>https://www.ncbi.nlm.nih.gov/pubmed/15781732 | Long-term serotonin administration induces heart valve disease in rats.</ref><ref>https://www.ncbi.nlm.nih.gov/pubmed/12466135 | Serotonin mechanisms in heart valve disease II: the 5-HT2 receptor and its signaling pathway in aortic valve interstitial cells.</ref> | ||