2C-T-7: Difference between revisions

Line 22:

2C-T-7's [[psychedelic]] effects have been shown to come from its efficacy at the [[Serotonin#The 5-HT system|5-HT<sub>2A</sub> receptor]] as a [[Agonist#Agonists|partial agonist]].<ref>Hallucinogen-like actions of 2,5-dimethoxy-4-(n)-propylthiophenethylamine (2C-T-7) in mice and rats | http://link.springer.com/article/10.1007%2Fs00213-005-0009-4</ref> However, the role of these interactions and how they result in the [[psychedelic]] experience continues to remain elusive.

With serious adverse effects seen on overdoses of this compound (potentially [[Serotonin Syndrome]]) and as the 2,5-desmethoxy derivative of 2C-T-7 has been shown to be a moderate monoamine oxidase A inhibitor{{~~citation needed~~}} and many of the amphetamine-analogs of the [[2C-T-x]] series are highly selective MAO-A inhibitors (with [[ALEPH-7]] being one of the most potent), this substance is widely thought to also have [[MAOI]] effects.

With serious adverse effects seen on overdoses of this compound (potentially [[Serotonin Syndrome]]) and as the 2,5-desmethoxy derivative of 2C-T-7 has been shown to be a moderate monoamine oxidase A inhibitor<ref name="WagmannBrandt2019">{{cite journal|last1=Wagmann|first1=Lea|last2=Brandt|first2=Simon D.|last3=Stratford|first3=Alexander|last4=Maurer|first4=Hans H.|last5=Meyer|first5=Markus R.|title=Interactions of phenethylamine-derived psychoactive substances of the 2C-series with human monoamine oxidases|journal=Drug Testing and Analysis|volume=11|issue=2|year=2019|pages=318–324|issn=19427603|doi=10.1002/dta.2494}}</ref> and many of the amphetamine-analogs of the [[2C-T-x]] series are highly selective MAO-A inhibitors (with [[ALEPH-7]] being one of the most potent), this substance is widely thought to also have [[MAOI]] effects.

==Subjective effects==

@@ Line 22: / Line 22: @@
 C-T-7's [[psychedelic]] effects have been shown to come from its efficacy at the [[Serotonin#The 5-HT system|5-HT<sub>2A</sub> receptor]] as a [[Agonist#Agonists|partial agonist]].<ref>Hallucinogen-like actions of 2,5-dimethoxy-4-(n)-propylthiophenethylamine (2C-T-7) in mice and rats | http://link.springer.com/article/10.1007%2Fs00213-005-0009-4</ref> However, the role of these interactions and how they result in the [[psychedelic]] experience continues to remain elusive.
-With serious adverse effects seen on overdoses of this compound (potentially [[Serotonin Syndrome]]) and as the 2,5-desmethoxy derivative of 2C-T-7 has been shown to be a moderate monoamine oxidase A inhibitor{{citation needed}} and many of the amphetamine-analogs of the [[2C-T-x]] series are highly selective MAO-A inhibitors (with [[ALEPH-7]] being one of the most potent), this substance is widely thought to also have [[MAOI]] effects.
+With serious adverse effects seen on overdoses of this compound (potentially [[Serotonin Syndrome]]) and as the 2,5-desmethoxy derivative of 2C-T-7 has been shown to be a moderate monoamine oxidase A inhibitor<ref name="WagmannBrandt2019">{{cite journal|last1=Wagmann|first1=Lea|last2=Brandt|first2=Simon D.|last3=Stratford|first3=Alexander|last4=Maurer|first4=Hans H.|last5=Meyer|first5=Markus R.|title=Interactions of phenethylamine-derived psychoactive substances of the 2C-series with human monoamine oxidases|journal=Drug Testing and Analysis|volume=11|issue=2|year=2019|pages=318–324|issn=19427603|doi=10.1002/dta.2494}}</ref> and many of the amphetamine-analogs of the [[2C-T-x]] series are highly selective MAO-A inhibitors (with [[ALEPH-7]] being one of the most potent), this substance is widely thought to also have [[MAOI]] effects.
 ==Subjective effects==