2C-H: Difference between revisions

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==Pharmacology==

There is no record of 2C-H trials in humans, as it would likely be destroyed by monoamine oxidase enzymes before causing any significant psychoactive effects.<ref> [[Alexander Shlulgin|Shulgin, Alexander]]; [[Ann Shulgin]] (September 1991). [https://www.erowid.org/library/books_online/pihkal/pihkal023.shtml PiHKAL: A Chemical Love Story.] Berkeley, California: Transform Press. ISBN 0-9630096-0-5. OCLC 25627628.</ref> Very little data exists about the pharmacological properties, metabolism, and toxicity of 2C-H. However, it has been shown to have binding affinity towards [[Serotonin#The_5-HT_system|5-HT2C]] and [[Serotonin#The_5-HT_system|5-HT2A]] [[receptor]]s in rats.<ref>2C-H BioAssay Results (PubChem) | https://pubchem.ncbi.nlm.nih.gov/compound/76632#section=BioAssay-Results</ref>

There is no record of 2C-H trials in humans, as it would likely be destroyed by monoamine oxidase enzymes before causing any significant psychoactive effects.<ref> [[Alexander Shlulgin|Shulgin, Alexander]]; [[Ann Shulgin]] (September 1991). [https://www.erowid.org/library/books_online/pihkal/pihkal023.shtml PiHKAL: A Chemical Love Story.] Berkeley, California: Transform Press. ISBN 0-9630096-0-5. OCLC 25627628.</ref> Very little data exists about the pharmacological properties, metabolism, and toxicity of 2C-H. However, it has been shown to have binding affinity towards [[Serotonin#The_5-HT_system|5-HT2C]] and [[Serotonin#The_5-HT_system|5-HT2A]] [[receptor]]s in rats.<ref>2C-H BioAssay Results (PubChem) | https://pubchem.ncbi.nlm.nih.gov/compound/76632#section=BioAssay-Results</ref> 2C-H has been shown to inhibit MAO-B activity by over 50% in experiments.<ref name="WagmannBrandt2019">{{cite journal|last1=Wagmann|first1=Lea|last2=Brandt|first2=Simon D.|last3=Stratford|first3=Alexander|last4=Maurer|first4=Hans H.|last5=Meyer|first5=Markus R.|title=Interactions of phenethylamine-derived psychoactive substances of the 2C-series with human monoamine oxidases|journal=Drug Testing and Analysis|volume=11|issue=2|year=2019|pages=318–324|issn=19427603|doi=10.1002/dta.2494}}</ref>

==Subjective effects==

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 ==Pharmacology==
-There is no record of 2C-H trials in humans, as it would likely be destroyed by monoamine oxidase enzymes before causing any significant psychoactive effects.<ref> [[Alexander Shlulgin|Shulgin, Alexander]]; [[Ann Shulgin]] (September 1991). [https://www.erowid.org/library/books_online/pihkal/pihkal023.shtml PiHKAL: A Chemical Love Story.] Berkeley, California: Transform Press. ISBN 0-9630096-0-5. OCLC 25627628.</ref> Very little data exists about the pharmacological properties, metabolism, and toxicity of 2C-H. However, it has been shown to have binding affinity towards [[Serotonin#The_5-HT_system|5-HT2C]] and [[Serotonin#The_5-HT_system|5-HT2A]] [[receptor]]s in rats.<ref>2C-H BioAssay Results (PubChem) | https://pubchem.ncbi.nlm.nih.gov/compound/76632#section=BioAssay-Results</ref>
+There is no record of 2C-H trials in humans, as it would likely be destroyed by monoamine oxidase enzymes before causing any significant psychoactive effects.<ref> [[Alexander Shlulgin|Shulgin, Alexander]]; [[Ann Shulgin]] (September 1991). [https://www.erowid.org/library/books_online/pihkal/pihkal023.shtml PiHKAL: A Chemical Love Story.] Berkeley, California: Transform Press. ISBN 0-9630096-0-5. OCLC 25627628.</ref> Very little data exists about the pharmacological properties, metabolism, and toxicity of 2C-H. However, it has been shown to have binding affinity towards [[Serotonin#The_5-HT_system|5-HT2C]] and [[Serotonin#The_5-HT_system|5-HT2A]] [[receptor]]s in rats.<ref>2C-H BioAssay Results (PubChem) | https://pubchem.ncbi.nlm.nih.gov/compound/76632#section=BioAssay-Results</ref> 2C-H has been shown to inhibit MAO-B activity by over 50% in experiments.<ref name="WagmannBrandt2019">{{cite journal|last1=Wagmann|first1=Lea|last2=Brandt|first2=Simon D.|last3=Stratford|first3=Alexander|last4=Maurer|first4=Hans H.|last5=Meyer|first5=Markus R.|title=Interactions of phenethylamine-derived psychoactive substances of the 2C-series with human monoamine oxidases|journal=Drug Testing and Analysis|volume=11|issue=2|year=2019|pages=318–324|issn=19427603|doi=10.1002/dta.2494}}</ref>
 ==Subjective effects==