1B-LSD: Difference between revisions

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==Chemistry==

[[File:Lysergamide1.png|thumb|right|215px||Substitutive structure of a generic lysergamide molecule.]]

1B-LSD is a molecule of the [[lysergamide]] family. It is similar to [[LSD]] and is named for the ~~propionyl~~ group bound to the nitrogen of the polycyclic indole group of LSD. ~~Propionyl consists~~ of the ~~carbonyl chain CH<sub>3</sub>CH<sub>2</sub>CO- bound~~ to ~~an amino group.~~

1B-LSD is a molecule of the [[lysergamide]] family. It is similar to [[LSD]] and is named for the butyryl group bound to the nitrogen of the polycyclic indole group of LSD.

1B-LSD ~~is homologous to [[ALD~~-~~52]], which holds an acetyl~~ group ~~bound to~~ the ~~nitrogen instead of~~ the ~~propionyl group bound at~~ the ~~same location. The structure of 1B-LSD contains a polycyclic group featuring a bicyclic hexahydro indole bound to a bicyclic quinoline group. At carbon 8 of~~ the ~~quinoline~~, ~~an N~~,~~N-diethyl carboxamide is bound~~.

The tetracyclic ergoline is characteristic of the chemical structure of ergot alkaloids. In contrast to LSD, 1B-LSD has an additional N1-butyryl group. Chemical modifications in the N1 position are among the most frequently performed changes in the ergoline system, as the Indole nitrogen is easily accessible for alkylations, acylations, Mannich reactions and Michael additions.

==Pharmacology==

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 ==Chemistry==
 [[File:Lysergamide1.png|thumb|right|215px||Substitutive structure of a generic lysergamide molecule.]]
-B-LSD is a molecule of the [[lysergamide]] family. It is similar to [[LSD]] and is named for the propionyl group bound to the nitrogen of the polycyclic indole group of LSD. Propionyl consists of the carbonyl chain CH<sub>3</sub>CH<sub>2</sub>CO- bound to an amino group.
+B-LSD is a molecule of the [[lysergamide]] family. It is similar to [[LSD]] and is named for the butyryl group bound to the nitrogen of the polycyclic indole group of LSD.
-B-LSD is homologous to [[ALD-52]], which holds an acetyl group bound to the nitrogen instead of the propionyl group bound at the same location. The structure of 1B-LSD contains a polycyclic group featuring a bicyclic hexahydro indole bound to a bicyclic quinoline group. At carbon 8 of the quinoline, an N,N-diethyl carboxamide is bound.
+The tetracyclic ergoline is characteristic of the chemical structure of ergot alkaloids. In contrast to LSD, 1B-LSD has an additional N1-butyryl group. Chemical modifications in the N1 position are among the most frequently performed changes in the ergoline system, as the Indole nitrogen is easily accessible for alkylations, acylations, Mannich reactions and Michael additions.
 ==Pharmacology==