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Template:DangerousInteractions/Psychedelics: Difference between revisions
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*'''[[UncertainInteraction::Cannabis|[[Cannabis]]]]''' - Cannabis has an unexpectedly strong and somewhat unpredictable synergy with the effects of psychedelics. Extreme caution is advised when using this combination as it can significantly increase the chances of a negative psychological reaction like [[anxiety]], [[paranoia]], [[panic attacks]], and [[psychosis]]. Users are advised to start off with only a fraction of their normal cannabis dose and take long breaks between hits to avoid over intake. | *'''[[UncertainInteraction::Cannabis|[[Cannabis]]]]''' - Cannabis has an unexpectedly strong and somewhat unpredictable synergy with the effects of psychedelics. Extreme caution is advised when using this combination as it can significantly increase the chances of a negative psychological reaction like [[anxiety]], [[paranoia]], [[panic attacks]], and [[psychosis]]. Users are advised to start off with only a fraction of their normal cannabis dose and take long breaks between hits to avoid over intake. | ||
*'''[https://en.wikipedia.org/wiki/Lithium_(medication) [[DangerousInteraction::Lithium]]]''' - Lithium is often prescribed as a treatment for bipolar disorder. It may possibly cause elevated risk of seizures and psychosis due to its [[Glutamate|glutaminergic]] and [[GABA|GABAergic]] effects.{{citation needed}} | |||
*'''[[UncertainInteraction::Stimulants|[[Stimulants]]]]''' (''[[amphetamines]], [[cathinones]], [[cocaine]], [[phenidates]]'', etc.) - Stimulants affect many parts of the brain and alter dopaminergic function. Combined with psychedelics, stimulation can turn into uncontrollable [[anxiety]], [[Panic attacks|panic]], [[thought loops]], and [[paranoia]]. This interaction may result in an elevated risk of [[mania]] and [[psychosis]].{{citation needed}} | *'''[[UncertainInteraction::Stimulants|[[Stimulants]]]]''' (''[[amphetamines]], [[cathinones]], [[cocaine]], [[phenidates]]'', etc.) - Stimulants affect many parts of the brain and alter dopaminergic function. Combined with psychedelics, stimulation can turn into uncontrollable [[anxiety]], [[Panic attacks|panic]], [[thought loops]], and [[paranoia]]. This interaction may result in an elevated risk of [[mania]] and [[psychosis]].{{citation needed}} | ||
*'''[[UnsafeInteraction::Tramadol|[[Tramadol]]]]''' - Tramadol lowers the seizure threshold<ref>Talaie, H., Panahandeh, R., Fayaznouri, M. R., Asadi, Z., & Abdollahi, M. (2009). Dose-independent occurrence of seizure with tramadol. Journal of Medical Toxicology, 5(2), 63-67. https://doi.org/10.1007/BF03161089</ref> and [[psychedelics]] may act as triggers for seizures in susceptible individuals.{{citation needed}} | *'''[[UnsafeInteraction::Tramadol|[[Tramadol]]]]''' - Tramadol lowers the seizure threshold<ref>Talaie, H., Panahandeh, R., Fayaznouri, M. R., Asadi, Z., & Abdollahi, M. (2009). Dose-independent occurrence of seizure with tramadol. Journal of Medical Toxicology, 5(2), 63-67. https://doi.org/10.1007/BF03161089</ref> and [[psychedelics]] may act as triggers for seizures in susceptible individuals.{{citation needed}} | ||