Codeine: Difference between revisions

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Codeine is the second most predominant alkaloid in [[opium]] (up to three percent).{{citation needed}} Although codeine can be extracted from natural sources, a semi-synthetic process is the primary source of codeine for pharmaceutical use. It is considered the prototype of the weak to midrange [[opioids]] ([[tramadol]], [[dextropropoxyphene]], [[dihydrocodeine]] and [[hydrocodone]].{{citation needed}}

Codeine is currently the most widely used opiate in the world,<ref>https://opiates.com/codeine</ref><ref>http://www.sciencedaily.com/releases/2010/03/100314150916.htm</ref> and is one of the most commonly used drugs overall according to numerous reports by organizations including the World Health Organization and its League of Nations predecessor agency. It is one of the most effective orally administered opioid analgesics and has a wide safety margin.

Codeine is currently the most widely used [[opiate]] in the world,<ref>https://opiates.com/codeine</ref><ref>http://www.sciencedaily.com/releases/2010/03/100314150916.htm</ref> and is one of the most commonly used drugs overall according to numerous reports by organizations including the World Health Organization and its League of Nations predecessor agency. It is one of the most effective orally administered opioid analgesics and has a wide safety margin.

Recreationally, it is usually purchased over the counter within painkillers that mix it with other more toxic substances. These can be separated using a [[Extraction of opioids from painkiller products|cold water extraction technique]].

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 Codeine is the second most predominant alkaloid in [[opium]] (up to three percent).{{citation needed}} Although codeine can be extracted from natural sources, a semi-synthetic process is the primary source of codeine for pharmaceutical use. It is considered the prototype of the weak to midrange [[opioids]] ([[tramadol]], [[dextropropoxyphene]], [[dihydrocodeine]] and [[hydrocodone]].{{citation needed}}
-Codeine is currently the most widely used opiate in the world,<ref>https://opiates.com/codeine</ref><ref>http://www.sciencedaily.com/releases/2010/03/100314150916.htm</ref> and is one of the most commonly used drugs overall according to numerous reports by organizations including the World Health Organization and its League of Nations predecessor agency. It is one of the most effective orally administered opioid analgesics and has a wide safety margin.
+Codeine is currently the most widely used [[opiate]] in the world,<ref>https://opiates.com/codeine</ref><ref>http://www.sciencedaily.com/releases/2010/03/100314150916.htm</ref> and is one of the most commonly used drugs overall according to numerous reports by organizations including the World Health Organization and its League of Nations predecessor agency. It is one of the most effective orally administered opioid analgesics and has a wide safety margin.
 Recreationally, it is usually purchased over the counter within painkillers that mix it with other more toxic substances. These can be separated using a [[Extraction of opioids from painkiller products|cold water extraction technique]].