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| ===Overdose=== | | ===Overdose=== |
| The risk of DOC overdose is present starting in or past the heavy dose range, although sensitive users may overdose at doses lower than these. Non-oral routes also seem to exhibit a higher chance of overdosing, perhaps owing to differences in bioavailability, potency and unpredictability of dosage and effects. Overdose effects typically include bizzare, [[delusion|delusional]] and sometimes violent behavior, [[amnesia]], [[tactile suppression|numbness]], [[confusion]] and [[anxiety]]. The user may not be able to communicate and can be severely agitated. At appropriately high doses, more serious side effects include [[panic attack]]s, [[seizures]], dangerously [[increased heart rate|elevated heart rate]], [[increased blood pressure|blood pressure]] and [[vasoconstriction]].{{citation needed}} Severe vasoconstriction typically develops to its peak several hours into the intoxication and may need medical assistance if blood flow is significantly cut off for extended periods of time.
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| In the event of an overdose, [[benzodiazepines]] can be administered to mitigate the hyperagitative effects.{{citation needed}} A powerful vasodilator may also need to be administered to prevent a hypertensive emergency, or in more serious cases, necrosis, organ failure and death from the resulting hypoxia.{{citation needed}} As a result, emergency medical services should always be sought in the event of a DOC overdose.
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| ===Dangerous interactions=== | | ===Dangerous interactions=== |
