|
|
| Line 201: |
Line 201: |
|
| |
|
| ===Overdose=== | | ===Overdose=== |
| Due to the very high potency and seemingly unpredictable effects the margin between a normal and an overdose of 25I-NBOMe is extremely small when compared to many other substances. The exact toxic dose is unclear since it seems to depend a lot on personal physiology, rather than predominantly dosage, but various anecdotal reports suggest dangerous side effects when exceeding 1000 μg and it possibly becoming lethal for the more sensitive people at roughly 2000 μg. Reports of other people surviving much higher doses, sometimes even without side effects has been documented as well. There is also the uncertainty of dosage on blotter paper since it is rather difficult to lay such an exact dosage. Insufflating, vaporizing or drinking tinctures of this substance is highly discouraged because of this.
| | {{NBOMeOD}} |
| | |
| The overdose effects of 25I-NBOMe are typically a dangerously high [[Increased heart rate|heart rate]], [[Increased blood pressure|blood pressure]], [[hyperthermia]] and significant [[vasoconstriction]]{{citation needed}} also accompanied by [[confusion]], [[delusions]], [[panic attack]]s, aggressive behavior, [[Tactile suppression|numbness]] or pain, [[amnesia]] and often [[seizure]]s. The risks in an overdose include anything from organ failure to cardiac arrest and death{{citation needed}}. There are also reports of people lethally injuring themselves or falling to death{{citation needed}}. [[Benzodiazepines]] or [[antipsychotics]] can help with the psychological effects during an overdose although medical attention should always be called in even a possible overdose of 25I-NBOMe.
| |
| | |
| Additionally, there are several proposed antidotes to an NBOMe overdose, including [[antipsychotics]] such as [[haloperidol]] and [[risperidone]], that cancel most psycholigical and possibly some of the physical effects, as well as blood pressure medications such as [[clonidine]], [[phentolamine]] and [[tolazoline]] that decrease heart rate and blood pressure and promote vasodilation. All of these are however only very sporadically reported to be a likely successful treatment in overdose cases. One should ''always'' consult a doctor first when using or mixing these and stick to the recommended dosages to avoid further complications.
| |
|
| |
|
| ===Dangerous interactions=== | | ===Dangerous interactions=== |
