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Selective serotonin reuptake inhibitor: Difference between revisions
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===Dangerous interactions=== | ===Dangerous interactions=== | ||
*'''[[Dextromethorphan]]''' - Dextromethorphan is a serotonin releaser as well as an SSRI, therefore has a potential to cause [[serotonin syndrome]], a potentially deadly condition caused by extremely high serotonin levels. Although serotonin syndrome caused by this combination is uncommon, it is strongly advised not to combine them, especially if either is at a high dose. | *'''[[Dextromethorphan]]''' - Dextromethorphan is a serotonin releaser as well as an SSRI, therefore has a potential to cause [[serotonin syndrome]], a potentially deadly condition caused by extremely high serotonin levels. Although serotonin syndrome caused by this combination is uncommon, it is strongly advised not to combine them, especially if either is at a high dose. | ||
*'''[[Empathogens]]''' - Combining SSRIs with serotonergic empathogens such as [[MDMA]], [[ | *'''[[Empathogens]]''' - Combining SSRIs with serotonergic empathogens such as [[MDMA]], [[mephedrone]], and AMT can result in [[serotonin syndrome]]. | ||
*'''[[Tramadol]]''' - Combining SSRIs with tramadol can result in [[serotonin syndrome]]. | *'''[[Tramadol]]''' - Combining SSRIs with tramadol can result in [[serotonin syndrome]]. | ||
*'''Other antidepresants''' - Combining SSRIs with other antidepressants such as tricyclic antidepressants and [[MAOI|MAOIs]] can result in [[serotonin syndrome]]. Non serotonergic antidepressants such as [[bupropion]] are not dangerous to combine with SSRIs. | *'''Other antidepresants''' - Combining SSRIs with other antidepressants such as tricyclic antidepressants and [[MAOI|MAOIs]] can result in [[serotonin syndrome]]. Non serotonergic antidepressants such as [[bupropion]] are not dangerous to combine with SSRIs. | ||