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Peganum harmala: Difference between revisions
>David Hedlund Added Desoxypeganine |
>David Hedlund Added the old alkaloid names in parentheses |
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*Desoxypeganine<ref>https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3841998/</ref> | *Desoxypeganine<ref>https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3841998/</ref> | ||
*[[Harmane]], 0.16%<ref name=partial>{{cite journal |vauthors=Hemmateenejad B, Abbaspour A, Maghami H, Miri R, Panjehshahin MR |title=Partial least squares-based multivariate spectral calibration method for simultaneous determination of beta-carboline derivatives in Peganum harmala seed extracts |journal=Anal. Chim. Acta |volume=575 |issue=2 |pages=290–9 |date=August 2006 |pmid=17723604 |doi=10.1016/j.aca.2006.05.093}}</ref> Harman is a selective MAO-A inhibitor.<ref>https://www.ncbi.nlm.nih.gov/pubmed/16139309</ref><ref>https://www.ncbi.nlm.nih.gov/pubmed/8149995</ref> | *[[Harmane]] (harman), 0.16%<ref name=partial>{{cite journal |vauthors=Hemmateenejad B, Abbaspour A, Maghami H, Miri R, Panjehshahin MR |title=Partial least squares-based multivariate spectral calibration method for simultaneous determination of beta-carboline derivatives in Peganum harmala seed extracts |journal=Anal. Chim. Acta |volume=575 |issue=2 |pages=290–9 |date=August 2006 |pmid=17723604 |doi=10.1016/j.aca.2006.05.093}}</ref> Harman is a selective MAO-A inhibitor.<ref>https://www.ncbi.nlm.nih.gov/pubmed/16139309</ref><ref>https://www.ncbi.nlm.nih.gov/pubmed/8149995</ref> | ||
*[[Harmine]], 0.44%<ref name=chroma>{{cite journal |vauthors=Pulpati H, Biradar YS, Rajani M |title=High-performance thin-layer chromatography densitometric method for the quantification of harmine, harmaline, vasicine, and vasicinone in Peganum harmala |journal=J AOAC Int |volume=91 |issue=5 |pages=1179–85 |year=2008 |pmid=18980138}}</ref>–1.84%<ref name=partial/>–4.3%<ref name=new1>{{cite journal |vauthors=Herraiz T, González D, Ancín-Azpilicueta C, Arán VJ, Guillén H |title=beta-Carboline alkaloids in Peganum harmala and inhibition of human monoamine oxidase (MAO) |journal=Food Chem. Toxicol. |volume=48 |issue=3 |pages=839–45 |date=March 2010 |pmid=20036304 |doi=10.1016/j.fct.2009.12.019}}</ref> Harmine is a nonselective MAO-A and MAO-B inhibitor. Also, the coatings of the seeds are said to contain large amounts of harmine.<ref name=cdfa>{{cite web|url= https://www.cdfa.ca.gov/plant/IPC/encycloweedia/weedinfo/peganum.htm |title=''African rue or Harmel'' |accessdate=2008-02-02 |publisher=www.cdfa.ca.gov }}</ref> | *[[Harmine]] (banisterine, telepathine), 0.44%<ref name=chroma>{{cite journal |vauthors=Pulpati H, Biradar YS, Rajani M |title=High-performance thin-layer chromatography densitometric method for the quantification of harmine, harmaline, vasicine, and vasicinone in Peganum harmala |journal=J AOAC Int |volume=91 |issue=5 |pages=1179–85 |year=2008 |pmid=18980138}}</ref>–1.84%<ref name=partial/>–4.3%<ref name=new1>{{cite journal |vauthors=Herraiz T, González D, Ancín-Azpilicueta C, Arán VJ, Guillén H |title=beta-Carboline alkaloids in Peganum harmala and inhibition of human monoamine oxidase (MAO) |journal=Food Chem. Toxicol. |volume=48 |issue=3 |pages=839–45 |date=March 2010 |pmid=20036304 |doi=10.1016/j.fct.2009.12.019}}</ref> Harmine is a nonselective MAO-A and MAO-B inhibitor. Also, the coatings of the seeds are said to contain large amounts of harmine.<ref name=cdfa>{{cite web|url= https://www.cdfa.ca.gov/plant/IPC/encycloweedia/weedinfo/peganum.htm |title=''African rue or Harmel'' |accessdate=2008-02-02 |publisher=www.cdfa.ca.gov }}</ref> | ||
*[[Harmaline]], 0.25%<ref name=partial/>–0.79%<ref name=chroma/>–5.6%<ref name=new1/> Harmaline is a [[RIMA]].<ref>{{ cite book | author = Massaro, E. J. | title = Handbook of Neurotoxicology | publisher = Humana Press | location = Totowa, NJ | year = 2002 | isbn = 0-89603-796-7 | url = https://books.google.com/books?id=2c2K-epbCDQC&pg=PA237&lpg=PA237&dq=harmaline+antidepressant | page = 237 }}</ref> | *[[Harmaline]] (harmidine), 0.25%<ref name=partial/>–0.79%<ref name=chroma/>–5.6%<ref name=new1/> Harmaline is a [[RIMA]].<ref>{{ cite book | author = Massaro, E. J. | title = Handbook of Neurotoxicology | publisher = Humana Press | location = Totowa, NJ | year = 2002 | isbn = 0-89603-796-7 | url = https://books.google.com/books?id=2c2K-epbCDQC&pg=PA237&lpg=PA237&dq=harmaline+antidepressant | page = 237 }}</ref> | ||
*[[Harmalol]], 0.6%<ref name=new1/>–3.90%<ref name=partial/> | *[[Harmalol]], 0.6%<ref name=new1/>–3.90%<ref name=partial/> | ||
*[[Tetrahydroharmine]], 0.1%<ref name=new1/> | *[[Tetrahydroharmine]] (THH), 0.1%<ref name=new1/> | ||
*Harmol<ref>https://www.ncbi.nlm.nih.gov/pubmed/12609665</ref> | *Harmol<ref>https://www.ncbi.nlm.nih.gov/pubmed/12609665</ref> | ||
*Vasicine (peganine),<ref name="nook">http://www.thenook.org/archives/tek/06332ott.html{{full citation needed|date=May 2013}}</ref> 0.25%<ref name=chroma/> | *Vasicine (peganine),<ref name="nook">http://www.thenook.org/archives/tek/06332ott.html{{full citation needed|date=May 2013}}</ref> 0.25%<ref name=chroma/> | ||