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Peganum harmala: Difference between revisions
>David Hedlund Added: Harman is a nonselective MAO-A inhibitor.<ref>https://www.ncbi.nlm.nih.gov/pubmed/16139309</ref> |
>David Hedlund Harman is a selective MAO-A inhibitor https://www.ncbi.nlm.nih.gov/pubmed/8149995 |
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Powdered syrian rue seeds act as a MAOI at doses of 2-5g. | Powdered syrian rue seeds act as a MAOI at doses of 2-5g. | ||
Syrian rue seeds contain several different harmala alkaloids at slightly varying percentages. Only some are monoamine oxidase A inhibitors. In one study, total harmala alkaloids were at least 5.9% of dried weight.<ref>http://www.phcogrev.com/article.asp?issn=0973-7847;year=2013;volume=7;issue=14;spage=199;epage=212;aulast=Moloudizargari</ref><ref>http://www.tandfonline.com/doi/abs/10.1080/15563650701323205</ref> | Syrian rue seeds contain several different harmala alkaloids at slightly varying percentages. Only some are monoamine oxidase A inhibitors. In one study, total harmala alkaloids were at least 5.9% of dried weight.<ref>http://www.phcogrev.com/article.asp?issn=0973-7847;year=2013;volume=7;issue=14;spage=199;epage=212;aulast=Moloudizargari</ref><ref>http://www.tandfonline.com/doi/abs/10.1080/15563650701323205</ref> | ||
*'''Harmane:''' 0.16%. Harman is a | *'''Harmane:''' 0.16%. Harman is a selective MAO-A inhibitor.<ref>https://www.ncbi.nlm.nih.gov/pubmed/16139309</ref><ref>https://www.ncbi.nlm.nih.gov/pubmed/8149995</ref> | ||
*'''Harmine:''' 0.44%. Harmine is a nonselective MAO-A and MAO-B inhibitor. The coatings of the seeds are said to contain large amounts of harmine. | *'''Harmine:''' 0.44%. Harmine is a nonselective MAO-A and MAO-B inhibitor. The coatings of the seeds are said to contain large amounts of harmine. | ||
*'''Harmaline:''' 0.25%. Harmaline is a "reversible inhibitor of MAO-A (RIMA).<ref>{{ cite book | author = Massaro, E. J. | title = Handbook of Neurotoxicology | publisher = Humana Press | location = Totowa, NJ | year = 2002 | isbn = 0-89603-796-7 | url = https://books.google.com/books?id=2c2K-epbCDQC&pg=PA237&lpg=PA237&dq=harmaline+antidepressant | page = 237 }}</ref> | *'''Harmaline:''' 0.25%. Harmaline is a "reversible inhibitor of MAO-A (RIMA).<ref>{{ cite book | author = Massaro, E. J. | title = Handbook of Neurotoxicology | publisher = Humana Press | location = Totowa, NJ | year = 2002 | isbn = 0-89603-796-7 | url = https://books.google.com/books?id=2c2K-epbCDQC&pg=PA237&lpg=PA237&dq=harmaline+antidepressant | page = 237 }}</ref> | ||