MiPLA: Difference between revisions
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==Subjective effects== | ==Subjective effects== | ||
MiPLA is commonly reported to be significantly shorter in its duration and less uncomfortable in both its [[Uncomfortable_physical_effects|negative physical side effects]] and general [[anxiety]]. | |||
{{Preamble/SubjectiveEffects}} | |||
{{effects/base | |||
|{{effects/physical| | |||
*'''[[Effect::Stimulation]]''' - In terms of its effects on the physical energy levels of the user, MiPLA is regarded as being able primarily stimulating in nature in the same vein as LSD. This is in distinction to other, more commonly used psychedelics such as [[psilocybin]] which are more consistent in producing [[sedation]] and [[muscle relaxation|relaxedness]]. | |||
*'''[[Effect::Spontaneous bodily sensations]]''' - The "body high" of MiPLA can be described as proportionally intense in comparison to its accompanying visual and cognitive effects. It behaves as a euphoric, fast-moving, sharp and location specific tingling sensation. For some, it is manifested spontaneously at different unpredictable points throughout the experience, but for most it maintains a steady presence that rises with the onset and hits its limit once the peak has been reached. In comparison to LSD, it is a little less sharp in the tingling sensations it produces as but is otherwise essentially indistinguishable. | |||
*'''[[Effect::Perception of bodily lightness]]''' - This component typically accompanies any feelings of [[stimulation]] that this compound can produce. | |||
*'''[[Effect::Physical euphoria]]''' - It should be noted that this effect is not as reliably induceable as it is with substances like [[stimulants]] or [[entactogens]], and can just as easily manifest as physical discomfort without any apparent reason. | |||
*'''[[Effect::Changes in felt bodily form]]''' - This effect is often accompanied by a sense of warmth or [[Unity and interconnectedness#Unity between the self and specific external systems|unity]] and usually occurs during and up to the peak of the experience or directly afterward. Users can feel as if they are physically part of or conjoined with other objects. This is usually reported as feeling comfortable and peaceful in its sensations. | |||
*'''[[Effect::Tactile enhancement]]''' - Feelings of enhanced tactile sensations are consistently present at moderate levels throughout most MiPLA trips. If [[Effect::8A Geometry|level 8A geometry]] is reached, an intense sensation of suddenly becoming aware of and being able to feel every single nerve ending across a person's entire body all at once becomes consistently present. | |||
*'''[[Effect::Temperature regulation suppression]]''' - This component can occur with the use of any lysergamide or psychedelic, but reports suggest it may be pronounced in MiPLA. It is highly advised that users of this compound, especially at heavier doses, monitor their bodily temperature and use techniques like hot showers or cold packs to regulate their core and brain temperature throughout the experience, and to generally always maintain proximity to a climate-controlled environment. | |||
*'''[[Effect::Increased bodily temperature]]''' | |||
*'''[[Effect::Nausea]]''' - Mild nausea is occasionally reported when this substance is consumed in moderate to high dosages, usually during the peak, and either passes soon after the user has vomited or gradually fades by itself as the peak sets in. | |||
*'''[[Effect::Stamina enhancement]]''' - This is generally mild in comparison to traditional [[stimulants]]. | |||
*'''[[Effect::Bodily control enhancement]]''' | |||
*'''[[Effect::Appetite suppression]]''' | |||
*'''[[Effect::Difficulty urinating]]''' | |||
*'''[[Effect::Increased blood pressure]]''' | |||
*'''[[Effect::Increased heart rate]]''' | |||
*'''[[Effect::Increased perspiration]]''' | |||
*'''[[Effect::Muscle contractions]]''' | |||
*'''[[Effect::Muscle spasms]]''' | |||
*'''[[Effect::Increased libido]]''' | |||
*'''[[Effect::Excessive yawning]]''' - This effect is significantly less pronounced than it is with [[psilocybin]] and its related compounds, the four-position [[Tryptamine#List of substituted tryptamines|substituted tryptamines]]. | |||
*'''[[Effect::Pupil dilation]]''' | |||
*'''[[Effect::Increased salivation]]''' | |||
*'''[[Effect::Seizure]]''' - The possibility of seizures is extrapolated from the seizures that have been reported following the use of [[LSD]]. They are thought to mainly be a risk in those who are genetically predisposed to them, particularly while accompanied by physically taxing conditions such as dehydration, fatigue or undernourishment. | |||
}} | |||
{{effects/visual| | |||
====Enhancements==== | |||
*'''[[Effect::Visual acuity enhancement]]''' | |||
*'''[[Effect::Colour enhancement]]''' | |||
*'''[[Effect::Pattern recognition enhancement]]''' | |||
====Distortions==== | |||
*'''[[Effect::Drifting]]''' ''([[Drifting#Melting|melting]], [[Drifting#Breathing|breathing]], [[Drifting#Morphing|morphing]] and [[Drifting#Flowing|flowing]])'' - In comparison to other psychedelics, this effect can be described as highly detailed yet cartoon-like in appearance. The distortions are slow and smooth in motion and fleeting in their appearance. This is nearly identical in appearance to the visual drifting which occurs under the influence of [[LSD]]. | |||
*'''[[Effect::After images]]''' | |||
*'''[[Effect::Tracers]]''' | |||
*'''[[Effect::Colour shifting]]''' | |||
*'''[[Effect::Depth perception distortions]]''' | |||
*'''[[Effect::Diffraction]]''' | |||
*'''[[Effect::Scenery slicing]]''' | |||
*'''[[Effect::Symmetrical texture repetition]]''' | |||
====[[Geometry]]==== | |||
The [[visual geometry]] evoked by MiPLA can be described as more similar in appearance to that of [[LSD]], [[2C-B]] or [[4-HO-MET]] than [[psilocin]], [[LSA]] or [[DMT]]. It can be comprehensively described through its [[Visual_effects:_Geometry#Variations|variations]] as primarily intricate in complexity, algorithmic in form, unstructured in organization, brightly lit, colourful and cartoonish in scheme, organic in feel, flat in shading, soft in its edges, large in size, slow in speed, smooth in motion, either angular or round in its corners, non-immersive in-depth and consistent in intensity. At higher dosages, it consistently results in states of [[Effect::Level 8B]] visual geometry over [[Level 8A]]. | |||
In comparison to LSD specifically, MiPLA's geometry tends to be more rounded in its corners, slightly softer in its edges, warmer in hue, and slightly less intricate in its form. Aside from this, it is otherwise identical in its appearance. | |||
====Hallucinatory states==== | |||
MiPLA is capable of producing a full range of low and high level hallucinatory states in a fashion that is a less consistent and reproducible than that of many other commonly used psychedelics such as [[psilocin]] or [[DMT]] but considerably more likely to when compared to that of [[LSD]]. This can feel similar to the hallucinations which occur with [[4-AcO-DMT]] but tends to occur almost exclusively at [[heavy|heavier]] [[dosage|doses]]. Some of these effects include: | |||
*'''[[Effect::Machinescapes]]''' | |||
*'''[[Effect::Transformations]]''' | |||
*'''[[Effect::Internal hallucination]]''' (''[[effect::autonomous entities]]''; ''[[effect::settings, sceneries, and landscapes]]''; ''[[effect::perspective hallucinations]]'' and ''[[effect::scenarios and plots]]'') - This effect is very consistent in dark environments at appropriately high dosages. They can be comprehensively described through their [[Visual_effects:_Internal_hallucinations#Variations|variations]] as lucid in believability, interactive in style, new experiences in content, autonomous in controllability, [[Geometry|geometry]]-based in style and occasionally of a personal, religious, spiritual, science-fiction, fantasy, surreal, nonsensical or transcendental nature in their overall theme. | |||
*'''[[Effect::External hallucination]]''' (''[[effect::autonomous entities]]''; ''[[effect::settings, sceneries, and landscapes]]''; ''[[effect::perspective hallucinations]]'' and ''[[effect::scenarios and plots]]'') | |||
}} | |||
|{{effects/cognitive| | |||
In comparison to other psychedelics such as [[psilocin]], [[LSA]] and [[ayahuasca]], MiPLA is significantly more stimulating and fast-paced in terms of the specific style of thought stream which it produces and contains a large number of potential effects associated with both psychedelic tryptamines and phenethylamines. In comparison to [[LSD]], it is often reported to be less [[anxiety]]-provoking and generally more emotionally comfortable and forgiving. | |||
The most prominent of these cognitive effects generally include: | |||
*'''[[Effect::Analysis enhancement]]''' - This effect is consistent in its manifestation and [[outrospection]] dominant. | |||
*'''[[Effect::Conceptual thinking]]''' | |||
*'''[[Effect::Cognitive euphoria]]''' - This component is, generally speaking less consistent and pronounced than it is with substances like [[psilocybin]] and [[MDMA]]. The mental euphoria experienced on MiPLA is usually simply due to an enhancement of the user’s current psychological and emotional state coupled with its more regularly occurring effect, [[physical euphoria]]. | |||
*'''[[Effect::Novelty enhancement]]''' | |||
*'''[[Effect::Immersion enhancement]]''' | |||
*'''[[Effect::Focus enhancement]]''' - This effect is experienced exclusively on low or [[Dosage#Threshold|threshold]] dosages and feels less forced than it does with [[stimulants]]. | |||
*'''[[Effect::Immersion enhancement]]''' | |||
*'''[[Effect::Motivation enhancement]]''' | |||
*'''[[Effect::Emotion enhancement]]''' | |||
*'''[[Effect::Increased music appreciation]]''' | |||
*'''[[Effect::Increased sense of humor]]''' | |||
**'''[[Effect::Laughter fits]]''' | |||
*'''[[Effect::Memory suppression]]''' | |||
**'''[[Effect::Ego death]]''' | |||
*'''[[Effect::Time distortion]]''' | |||
*'''[[Effect::Déjà vu]]''' | |||
*'''[[Effect::Delusion]]''' | |||
*'''[[Effect::Thought acceleration]]''' | |||
*'''[[Effect::Thought loops]]''' | |||
*'''[[Effect::Wakefulness]]''' | |||
}} | |||
{{effects/auditory| | |||
*'''[[Effect::Auditory distortion]]''' | |||
*'''[[Effect::Auditory enhancement]]''' | |||
*'''[[Effect::Auditory hallucination]]''' | |||
}} | |||
{{effects/transpersonal| | |||
*'''[[Effect::Existential self-realization]]''' | |||
*'''[[Effect::Unity and interconnectedness]]''' | |||
}} | |||
}} | |||
===Combination effects=== | |||
*'''[[Alcohol]]''' - Alcohol's central depressant effects can counteract some of the anxiety and bodily tension produced by MiPLA. However, alcohol can cause [[dehydration]], [[nausea]] and [[physical fatigue]] which can negatively impact the tone of the trip. Users are advised to pace themselves and drink a portion of their usual amount. | |||
*'''[[Benzodiazepines]]''' - Benzodiazepines are highly effective at reducing the intensity of MiPLA's effects through the general suppression of brain activity. | |||
*'''[[Cannabis]]''' - Cannabis strongly intensifies the sensory and cognitive effects of MiPLA. Extreme caution is advised when using this combination as it can significantly increase the chances of a negative psychological reaction like [[anxiety]], [[confusion]] and [[psychosis]]. Users are advised to start off with only a fraction of their usual cannabis dose and take long breaks between hits to avoid over intake. | |||
*'''[[Dissociatives]]''' - MiPLA enhances the cognitive, visual and general hallucinatory effects of dissociatives. Dissociative-induced [[Visual_disconnection#Holes.2C_spaces_and_voids|holes, spaces, and voids]] and [[internal hallucinations]] become more vivid and intense on MiPLA. These effects correspond with an increased risk of [[confusion]], [[delusions]], and [[psychosis]]. | |||
*'''[[MDMA]]''' - MiPLA and MDMA are highly synergistic and mutually enhance each other's physical, cognitive, and visual effects. The synergy between these substances is unpredictable so it is advised to start with markedly lower doses than one would take for each individually. There is some evidence that suggests that co-administration of LSD with MDMA increases the neurotoxicity of the latter,<ref>Armstrong, B. D., Paik, E., Chhith, S., Lelievre, V., Waschek, J. A., & Howard, S. G. (2004). Potentiation of (DL)‐3, 4‐methylenedioxymethamphetamine (MDMA)‐induced toxicity by the serotonin 2A receptor partial agonist d‐lysergic acid diethylamide (MiPLA), and the protection of same by the serotonin 2A/2C receptor antagonist MDL 11,939. Neuroscience Research Communications, 35(2), 83-95. https://doi.org/10.1002/nrc.20023</ref><ref>Potentiation of MDMA-induced dopamine release and serotonin neurotoxicity by 5-HT2 receptor agonists | https://indiana.pure.elsevier.com/en/publications/potentiation-of-34-methylenedioxymethamphetamine-induced-dopamine</ref><ref>Ecstasy induces apoptosis via 5-HT(2A)-receptor stimulation in cortical neurons. | https://www.ncbi.nlm.nih.gov/pubmed/17572501</ref> and this may extend to MiPLA. | |||
===Experience reports=== | |||
There are currently {{#ask:[[Category:MiPLA]][[Category:Experience]] | format=count}} anecdotal reports which describe the effects of this compound within our [[experience index]]. | |||
{{#ask: [[Category:MiPLA]][[Category:Experience]]|format=ul|Columns=1}} | |||
Additional experience reports can be found here: | |||
* [https://www.erowid.org/experiences/subs/exp_ALLAD.shtml Erowid Experience Vaults: MiPLA] | |||
==Literature== | ==Literature== |