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5-MeO-MiPT: Difference between revisions
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{{SubstanceBox/5-MeO-MiPT}} | {{SubstanceBox/5-MeO-MiPT}} | ||
'''5-Methoxy-N-methyl-N-isopropyltryptamine''' (also known as '''5-MeO-MiPT''' | '''5-Methoxy-N-methyl-N-isopropyltryptamine''' (also known as '''5-MeO-MiPT''' and '''moxy''') is a lesser-known [[psychoactive class::psychedelic]] substance of the [[chemical class::tryptamine]] class. 5-MeO-MiPT is chemically related to tryptamines like [[5-MeO-DMT]] and [[5-MeO-DiPT]]. It produces its psychoactive effects through activity at [[serotonin]] [[receptors]] in the brain. | ||
5-MeO-MiPT | The synthesis and pharmacology of 5-MeO-MiPT was first reported in 1985 by David Repke and Alexander Shulgin.<ref>Repke, D. B., Grotjahn, D. B., & Shulgin, A. T. (1985). Psychotomimetic N-methyl-N-isopropyltryptamines. Effects of variation of aromatic oxygen substituents. ''Journal of medicinal chemistry'', ''28''(7), 892-896. PMID: 4009612</ref> Its effects in humans was documented in Shulgin's book [[TiHKAL]] ("Tryptamines I Have Known and Loved"). | ||
Anecdotal reports | Anecdotal reports describe 5-MeO-MiPT's effects as highly [[stimulating]] and mildly [[entactogenic]], lacking in typical psychedelic visual distortions. Many users report strong physical and tactile effects that serve to [[increased libido|enhance libido]] and sexual pleasure. An unpleasant "body load" is also often reported at common to high doses, marked by muscle tension and nausea. | ||
Very little is known about the pharmacological properties, metabolism and toxicity of | Very little is known about the pharmacological properties, metabolism and toxicity of 5-MeO-MiPT, and it has a limited history of human use. It has been sold online as a [[research chemical]]. It is highly advised to use harm reduction practices when using this substance. | ||
==Chemistry== | ==Chemistry== | ||
5-MeO-MiPT or 5-methoxy-N-methyl-N-isopropyltryptamine is a synthetic indole alkaloid molecule of the [[tryptamine]] class. Tryptamines share a core structure comprised of a bicylic indole heterocycle attached at R<sub>3</sub> to an amino group via an ethyl side chain. 5-MeO-MiPT is substituted at R<sub>5</sub> of its indole heterocycle with a methoxy (MeO) functional group CH<sub>3</sub>O−; it also contains a methyl group and an isopropyl chain bound to the terminal amine R<sub>N</sub> of its tryptamine backbone (MiPT). 5-MeO-MiPT is the N-substituted isopropyl homologue of [[5-MeO-DMT]].<ref>http://isomerdesign.com/PiHKAL/read.php?domain=tk&id=40</ref> | 5-MeO-MiPT, or 5-methoxy-N-methyl-N-isopropyltryptamine, is a synthetic indole alkaloid molecule of the [[tryptamine]] class. Tryptamines share a core structure comprised of a bicylic indole heterocycle attached at R<sub>3</sub> to an amino group via an ethyl side chain. 5-MeO-MiPT is substituted at R<sub>5</sub> of its indole heterocycle with a methoxy (MeO) functional group CH<sub>3</sub>O−; it also contains a methyl group and an isopropyl chain bound to the terminal amine R<sub>N</sub> of its tryptamine backbone (MiPT). | ||
5-MeO-MiPT is the N-substituted isopropyl homologue of [[5-MeO-DMT]].<ref>http://isomerdesign.com/PiHKAL/read.php?domain=tk&id=40</ref> | |||
==Pharmacology== | ==Pharmacology== | ||
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==Subjective effects== | ==Subjective effects== | ||
5-MeO-MiPT can be taken via oral ingestion or it can be smoked. When ingested orally, the visual and sensory effects are reported to become more prominent. The experience can be broken up into two stages; the first half feels [[stimulant|stimulating]] and [[entactogens|entactogenic]] whilst the second half feels more similar to a traditional [[tryptamine]] [[psychedelic]] like psilocybin mushrooms or LSD. When smoked, the physically and cognitively stimulating effects become emphasized. | |||
{{Preamble/SubjectiveEffects}} | {{Preamble/SubjectiveEffects}} | ||
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==Legal status== | ==Legal status== | ||
*'''Brazil''' - | *'''Brazil''': 5-MeO-MiPT is illegal to produce, sell, or possess as it is listed on Portaria SVS/MS nº 344.<ref>http://portal.anvisa.gov.br/documents/10181/3115436/%281%29RDC_130_2016_.pdf/fc7ea407-3ff5-4fc1-bcfe-2f37504d28b7</ref> | ||
*'''China:''' The drug is controlled as a Category I psychotropic substance and is illegal to sell, buy, import, export, and manufacture.<ref>Erowid China Psychoactive Law Update: September 2015 | https://www.erowid.org/psychoactives/law/countries/china/china_law_2015_09_27_list_of_newly_controlled_chemicals.pdf</ref> | *'''China:''' The drug is controlled as a Category I psychotropic substance and is illegal to sell, buy, import, export, and manufacture.<ref>Erowid China Psychoactive Law Update: September 2015 | https://www.erowid.org/psychoactives/law/countries/china/china_law_2015_09_27_list_of_newly_controlled_chemicals.pdf</ref> | ||
*'''Finland:''' 5-MeO-MiPT was banned in Finland in December 2014.<ref>Finland's Prohibited Psychoactive Substances: December 19, 2014. https://www.erowid.org/psychoactives/law/countries/finland/finland_law1_2014.pdf</ref> | *'''Finland:''' 5-MeO-MiPT was banned in Finland in December 2014.<ref>Finland's Prohibited Psychoactive Substances: December 19, 2014. https://www.erowid.org/psychoactives/law/countries/finland/finland_law1_2014.pdf</ref> | ||
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==References== | ==References== | ||
<references/> | <references /> | ||
[[Category:Psychoactive substance]] | [[Category:Psychoactive substance]] | ||
[[Category:Research chemical]] | [[Category:Research chemical]] | ||