LSA: Difference between revisions

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LSA, or d-lysergic acid amide, is an organic alkaloid belonging to the [[lysergamide]] class. The chemical structure of LSA contains a core structure of lysergic acid with an amine functional group bound to RN. The structure of lysergic acid is composed of a bicyclic hexahydroindole fused to a bicyclic quinoline group (lysergic acid). At carbon 8 of the quinoline, an acetamide group is bound. LSA is additionally substituted at carbon 6 with a methyl group.

LSA is a chiral compound with two stereocenters at R5 and R8. LSA, also called (+)-D-LSA, has an absolute configuration of (5''R'', 8''R''). The three other stereoisomers of LSA do not have psychoactive properties. LSA is structurally analogous to LSD, with the exception being that LSA lacks the diethyl substitution of LSD at RN of its carboxamide group.

LSA is a chiral compound with two stereocenters at R5 and R8. LSA, also called (+)-D-LSA, has an absolute configuration of (5''R'', 8''R''). The three other stereoisomers of LSA do not have psychoactive properties. LSA is structurally analogous to LSD, with the exception being that LSA lacks the diethyl substitution of LSD at RN of its carboxamide group. It can be used as a precursor to LSD.

==Pharmacology==

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 LSA, or d-lysergic acid amide, is an organic alkaloid belonging to the [[lysergamide]] class. The chemical structure of LSA contains a core structure of lysergic acid with an amine functional group bound to R<sub>N</sub>. The structure of lysergic acid is composed of a bicyclic hexahydroindole fused to a bicyclic quinoline group (lysergic acid). At carbon 8 of the quinoline, an acetamide group is bound. LSA is additionally substituted at carbon 6 with a methyl group.
-LSA is a chiral compound with two stereocenters at R<sub>5</sub> and R<sub>8</sub>. LSA, also called (+)-D-LSA, has an absolute configuration of (5''R'', 8''R''). The three other stereoisomers of LSA do not have psychoactive properties. LSA is structurally analogous to LSD, with the exception being that LSA lacks the diethyl substitution of LSD at R<sub>N</sub> of its carboxamide group.
+LSA is a chiral compound with two stereocenters at R<sub>5</sub> and R<sub>8</sub>. LSA, also called (+)-D-LSA, has an absolute configuration of (5''R'', 8''R''). The three other stereoisomers of LSA do not have psychoactive properties. LSA is structurally analogous to LSD, with the exception being that LSA lacks the diethyl substitution of LSD at R<sub>N</sub> of its carboxamide group. It can be used as a precursor to LSD.
 ==Pharmacology==