Salvinorin A: Difference between revisions

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*'''[[Effect::Synaesthesia]]'''

}}

~~===Classification===~~

Currently, the scientific literature classifies salvinorin A as a [[hallucinogen]]. However, there is additional debate as to whether it can correctly be labeled as a [[dissociative]] or an atypical dissociative with some [[psychedelic]] and even [[deliriant|delirious]] qualities.{{citation needed}}

Although salvia shares states of hallucinatory structures and out-of-body experiences commonly reported with typical dissociatives ([[NMDA receptor antagonist]]s), this is arguably not sufficient so that it falls under the same classification. For example, the hallucinatory structures (although similar) are vastly different in their style and complexity. Alongside of this, the out-of-body experiences commonly reported with dissociatives are presumed to be triggered by the way in which NMDA receptor antagonists block signals to the conscious mind from other parts of the brain. This is accompanied by a distinctive feeling of dissociation, disconnection and detachment which is not present on salvia as it works on an entirely different set of receptors, the function of which in the human brain is almost entirely unknown.{{citation needed}}

The effects of salvia have a subjectively unique style and pharmacology that is not found within any other category of [[hallucinogen]], this has led many within the [[psychonaut]] community assert that it deserves recognition for falling into an entirely new class of its own. Any compound within this subjective and pharmacological class could potentially be referred to as a "salviagenic". This would also include various other similar analogues such as [[Salvinorin B methoxymethyl ether|Salvinorin B]] and many others.<ref>

~~Salvinorin Analogues; Beyond Salvinorin A (DMT Nexus) | https://www.dmt-nexus.me/forum/default.aspx?g=posts&t=4823</ref>~~

===Experience reports===

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A [[Hot water extraction from dried Salvia Divinorum leaves|tea]] can be made by crushing 3–4 g of dried leaves and boiling them for 5 minutes. Afterwards, let it simmer for around 15 minutes. Salvinorin A is not orally active, so the tea has to be kept in the mouth for around 15–20 seconds for each sip. This tea, if properly brewed and ingested, can produce a trance-like state when closing the eyes and up to an entire night of vivid and intense dreams along with occasional closed eye visuals.

==~~Preparation methods~~==

==Classification==

~~Preparation methods for~~ this ~~compound~~ within ~~our~~ [[~~tutorial index~~]] include:

Currently, the scientific literature classifies salvinorin A as a [[hallucinogen]]. However, there is additional debate as to whether it can correctly be labeled as a [[dissociative]] or an atypical dissociative with some [[psychedelic]] and even [[deliriant|delirious]] qualities.{{citation needed}}

* [[~~Hot water extraction from dried Salvia Divinorum leaves~~]]

Although salvia shares states of hallucinatory structures and out-of-body experiences commonly reported with typical dissociatives ([[NMDA receptor antagonist]]s), this is arguably not sufficient so that it falls under the same classification. For example, the hallucinatory structures (although similar) are vastly different in their style and complexity. Alongside of this, the out-of-body experiences commonly reported with dissociatives are presumed to be triggered by the way in which NMDA receptor antagonists block signals to the conscious mind from other parts of the brain. This is accompanied by a distinctive feeling of dissociation, disconnection and detachment which is not present on salvia as it works on an entirely different set of receptors, the function of which in the human brain is almost entirely unknown.{{citation needed}}

The effects of salvia have a subjectively unique style and pharmacology that is not found within any other category of [[hallucinogen]], this has led many within the [[psychonaut]] community assert that it deserves recognition for falling into an entirely new class of its own. Any compound within this subjective and pharmacological class could potentially be referred to as a "salviagenic". This would also include various other similar analogues such as [[Salvinorin B methoxymethyl ether|Salvinorin B]] and many others.<ref>

Salvinorin Analogues; Beyond Salvinorin A (DMT Nexus) | https://www.dmt-nexus.me/forum/default.aspx?g=posts&t=4823</ref>

==Research==

Salvinorin A is currently being researched in relation to its properties as an anti-addiction drug, and several analogs with improved pharmacokinetic profiles have been shown to have anti-addictive effects as well.<ref>http://www.ncbi.nlm.nih.gov/pubmed/24484985</ref>

==Toxicity and harm potential==

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Tolerance to the effects of salvinorin A does not occur. In fact, many users report that the effects of this substance can actually become stronger over time and with repeated usage (a phenomenon known as "[[reverse tolerance]]"). Due to its unique set of target receptors, salvinorin A presents cross-tolerance with [[Cross-tolerance::no other [[hallucinogen]]s]].

==~~Legality~~==

==Legal status==

*'''Australia:''' Possession and sale is illegal.{{citation needed}}

*'''Austria:''' Salvinorin A is illegal to possess, produce and sell under the NPSG (Neue-Psychoaktive-Substanzen-Gesetz Österreich).{{citation needed}}

@@ Line 87: / Line 87: @@
 *'''[[Effect::Synaesthesia]]'''
 }}
 }}
-===Classification===
-Currently, the scientific literature classifies salvinorin A as a [[hallucinogen]]. However, there is additional debate as to whether it can correctly be labeled as a [[dissociative]] or an atypical dissociative with some [[psychedelic]] and even [[deliriant|delirious]] qualities.{{citation needed}}
-Although salvia shares states of hallucinatory structures and out-of-body experiences commonly reported with typical dissociatives ([[NMDA receptor antagonist]]s), this is arguably not sufficient so that it falls under the same classification. For example, the hallucinatory structures (although similar) are vastly different in their style and complexity. Alongside of this, the out-of-body experiences commonly reported with dissociatives are presumed to be triggered by the way in which NMDA receptor antagonists block signals to the conscious mind from other parts of the brain. This is accompanied by a distinctive feeling of dissociation, disconnection and detachment which is not present on salvia as it works on an entirely different set of receptors, the function of which in the human brain is almost entirely unknown.{{citation needed}}
-The effects of salvia have a subjectively unique style and pharmacology that is not found within any other category of [[hallucinogen]], this has led many within the [[psychonaut]] community assert that it deserves recognition for falling into an entirely new class of its own. Any compound within this subjective and pharmacological class could potentially be referred to as a "salviagenic". This would also include various other similar analogues such as [[Salvinorin B methoxymethyl ether|Salvinorin B]] and many others.<ref>
-Salvinorin Analogues; Beyond Salvinorin A (DMT Nexus) | https://www.dmt-nexus.me/forum/default.aspx?g=posts&t=4823</ref>
 ===Experience reports===
@@ Line 131: / Line 123: @@
 A [[Hot water extraction from dried Salvia Divinorum leaves|tea]] can be made by crushing 3&ndash;4&nbsp;g of dried leaves and boiling them for 5 minutes. Afterwards, let it simmer for around 15 minutes. Salvinorin A is not orally active, so the tea has to be kept in the mouth for around 15&ndash;20 seconds for each sip. This tea, if properly brewed and ingested, can produce a trance-like state when closing the eyes and up to an entire night of vivid and intense dreams along with occasional closed eye visuals.
-==Preparation methods==
+==Classification==
-Preparation methods for this compound within our [[tutorial index]] include:
+Currently, the scientific literature classifies salvinorin A as a [[hallucinogen]]. However, there is additional debate as to whether it can correctly be labeled as a [[dissociative]] or an atypical dissociative with some [[psychedelic]] and even [[deliriant|delirious]] qualities.{{citation needed}}
-* [[Hot water extraction from dried Salvia Divinorum leaves]]
+Although salvia shares states of hallucinatory structures and out-of-body experiences commonly reported with typical dissociatives ([[NMDA receptor antagonist]]s), this is arguably not sufficient so that it falls under the same classification. For example, the hallucinatory structures (although similar) are vastly different in their style and complexity. Alongside of this, the out-of-body experiences commonly reported with dissociatives are presumed to be triggered by the way in which NMDA receptor antagonists block signals to the conscious mind from other parts of the brain. This is accompanied by a distinctive feeling of dissociation, disconnection and detachment which is not present on salvia as it works on an entirely different set of receptors, the function of which in the human brain is almost entirely unknown.{{citation needed}}
+The effects of salvia have a subjectively unique style and pharmacology that is not found within any other category of [[hallucinogen]], this has led many within the [[psychonaut]] community assert that it deserves recognition for falling into an entirely new class of its own. Any compound within this subjective and pharmacological class could potentially be referred to as a "salviagenic". This would also include various other similar analogues such as [[Salvinorin B methoxymethyl ether|Salvinorin B]] and many others.<ref>
+Salvinorin Analogues; Beyond Salvinorin A (DMT Nexus) | https://www.dmt-nexus.me/forum/default.aspx?g=posts&t=4823</ref>
+==Research==
+Salvinorin A is currently being researched in relation to its properties as an anti-addiction drug, and several analogs with improved pharmacokinetic profiles have been shown to have anti-addictive effects as well.<ref>http://www.ncbi.nlm.nih.gov/pubmed/24484985</ref>
 ==Toxicity and harm potential==
@@ Line 147: / Line 146: @@
 Tolerance to the effects of salvinorin A does not occur. In fact, many users report that the effects of this substance can actually become stronger over time and with repeated usage (a phenomenon known as "[[reverse tolerance]]"). Due to its unique set of target receptors, salvinorin A presents cross-tolerance with [[Cross-tolerance::no other [[hallucinogen]]s]].
-==Legality==
+==Legal status==
 *'''Australia:''' Possession and sale is illegal.{{citation needed}}
 *'''Austria:'''	Salvinorin A is illegal to possess, produce and sell under the NPSG (Neue-Psychoaktive-Substanzen-Gesetz Österreich).{{citation needed}}