Talk:Tianeptine: Difference between revisions

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::{{Ping|Fitdisk}} Hello Fitdisk, thanks for taking the time to share your thoughts.

I get what you mean when you say tianeptine feels like it enhances creativity. Opioids and drugs with opioid activity have long been reported by various users to enable the output of creative and artistic works. Many artists, musicians and writers have attributed creative properties to these drugs.

::I get what you mean when you say tianeptine feels like it enhances creativity. Opioids and drugs with opioid activity have long been reported by various users to enable the output of creative and artistic works. Many artists, musicians and writers have attributed creative properties to these drugs.

However, I think it is important to keep in mind how difficult it is to disentangle the enhancement of motivation in those pre-existing with creative dispositions (likely as a byproduct of euphoria and anxyiolysis) versus the enhancement of a separate creative faculty. The basis for the effect only has a solid neurobiological grounding for setotonergic psychedelics and likely relates to their neuroplasticity-promoting properties. Opioids by contrast have a more dopaminergic nature, acting on the brains' motivation and reward pathways, and don't exhibit a clear mechanism by which it can induce fundamentally novel brain activity. I think it's more likely that they relieve the depression and anxiety that inflicts many creative types and therefore clears obstruction to creative productivity.

::However, I think it is important to keep in mind how difficult it is to disentangle the enhancement of motivation in those pre-existing with creative dispositions (likely as a byproduct of euphoria and anxyiolysis) versus the enhancement of a separate creative faculty. The basis for the effect only has a solid neurobiological grounding for setotonergic psychedelics and likely relates to their neuroplasticity-promoting properties. Opioids by contrast have a more dopaminergic nature, acting on the brains' motivation and reward pathways, and don't exhibit a clear mechanism by which it can induce fundamentally novel brain activity. I think it's more likely that they relieve the depression and anxiety that inflicts many creative types and therefore clears obstruction to creative productivity.

However, now that I think about it... tianeptine is distinct from other opioids in that it does possess setotonergic activity. So perhaps you're onto something here. I think what needs to happen is more comparison and analysis from those who have subjective experiences of enhanced creativity between tianeptine and more typical opioids. If tianeptine can be convincingly asserted to increase creativity that other opioids do not in the same subject group, it can potentially be added to this article. --[[User:Clarity|Clarity]] ([[User talk:Clarity|talk]]) 21:53, 22 May 2018 (UTC)

::However, now that I think about it... tianeptine is distinct from other opioids in that it does possess setotonergic activity. So perhaps you're onto something here. I think what needs to happen is more comparison and analysis from those who have subjective experiences of enhanced creativity between tianeptine and more typical opioids. If tianeptine can be convincingly asserted to increase creativity that other opioids do not in the same subject group, it can potentially be added to this article. --[[User:Clarity|Clarity]] ([[User talk:Clarity|talk]]) 21:53, 22 May 2018 (UTC)

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 ::{{Ping|Fitdisk}} Hello Fitdisk, thanks for taking the time to share your thoughts.
-I get what you mean when you say tianeptine feels like it enhances creativity. Opioids and drugs with opioid activity have long been reported by various users to enable the output of creative and artistic works. Many artists, musicians and writers have attributed creative properties to these drugs.
+::I get what you mean when you say tianeptine feels like it enhances creativity. Opioids and drugs with opioid activity have long been reported by various users to enable the output of creative and artistic works. Many artists, musicians and writers have attributed creative properties to these drugs.
-However, I think it is important to keep in mind how difficult it is to disentangle the enhancement of motivation in those pre-existing with creative dispositions (likely as a byproduct of euphoria and anxyiolysis) versus the enhancement of a separate creative faculty. The basis for the effect only has a solid neurobiological grounding for setotonergic psychedelics and likely relates to their neuroplasticity-promoting properties. Opioids by contrast have a more dopaminergic nature, acting on the brains' motivation and reward pathways, and don't exhibit a clear mechanism by which it can induce fundamentally novel brain activity. I think it's more likely that they relieve the depression and anxiety that inflicts many creative types and therefore clears obstruction to creative productivity.
+::However, I think it is important to keep in mind how difficult it is to disentangle the enhancement of motivation in those pre-existing with creative dispositions (likely as a byproduct of euphoria and anxyiolysis) versus the enhancement of a separate creative faculty. The basis for the effect only has a solid neurobiological grounding for setotonergic psychedelics and likely relates to their neuroplasticity-promoting properties. Opioids by contrast have a more dopaminergic nature, acting on the brains' motivation and reward pathways, and don't exhibit a clear mechanism by which it can induce fundamentally novel brain activity. I think it's more likely that they relieve the depression and anxiety that inflicts many creative types and therefore clears obstruction to creative productivity.
-However, now that I think about it... tianeptine is distinct from other opioids in that it does possess setotonergic activity. So perhaps you're onto something here. I think what needs to happen is more comparison and analysis from those who have subjective experiences of enhanced creativity between tianeptine and more typical opioids. If tianeptine can be convincingly asserted to increase creativity that other opioids do not in the same subject group, it can potentially be added to this article. --[[User:Clarity|Clarity]] ([[User talk:Clarity|talk]]) 21:53, 22 May 2018 (UTC)
+::However, now that I think about it... tianeptine is distinct from other opioids in that it does possess setotonergic activity. So perhaps you're onto something here. I think what needs to happen is more comparison and analysis from those who have subjective experiences of enhanced creativity between tianeptine and more typical opioids. If tianeptine can be convincingly asserted to increase creativity that other opioids do not in the same subject group, it can potentially be added to this article. --[[User:Clarity|Clarity]] ([[User talk:Clarity|talk]]) 21:53, 22 May 2018 (UTC)