Serotonin: Difference between revisions
>Unity Moved links in References section to 'External links'. Added 5-HTP link under 'See also'. |
>Unity Removed unsourced and inaccurate statement about serotonin causing cardiotoxicity. This is probably meant to refer to 5-HTP. Humans would not have functioning hearts if serotonin, an endogenous substance, was actually cardiotoxic. |
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[[File:Serotonin.svg|300px|thumb|right|Skeletal formula of serotonin molecule.]] | [[File:Serotonin.svg|300px|thumb|right|Skeletal formula of a serotonin molecule.]] | ||
'''Serotonin''', also known as '''5-hydroxytryptamine''' ('''5-HT'''), is a [[monoamine]] [[neurotransmitter|neurotransmitter]] affecting the [[serotonin]] [[receptors]] (5-HT<sub>1-7</sub>). Serotonin is primarily found in the gastrointestinal tract, platelets, and in the central nervous system of animals including humans. It is popularly thought to be a contributor to feelings of well-being and happiness. | '''Serotonin''', also known as '''5-hydroxytryptamine''' ('''5-HT'''), is a [[monoamine]] [[neurotransmitter|neurotransmitter]] affecting the [[serotonin]] [[receptors]] (5-HT<sub>1-7</sub>). Serotonin is primarily found in the gastrointestinal tract, platelets, and in the central nervous system of animals including humans. It is popularly thought to be a contributor to feelings of well-being and happiness. | ||
Approximately 90% of the human body's total serotonin is located in the digestive system, where it is used to regulate intestinal movements. The remainder is synthesized in serotonergic [[neurons]] of the CNS, where it has various functions. These include the regulation of mood, appetite, heart rate and sleep | Approximately 90% of the human body's total serotonin is located in the digestive system, where it is used to regulate intestinal movements. The remainder is synthesized in serotonergic [[neurons]] of the CNS, where it has various functions. These include the regulation of mood, appetite, heart rate and sleep. | ||
Serotonin also has some cognitive functions, including memory and learning. In the blood, it serves as a [[vasoconstriction|vasoconstrictor]], and could be attributed as the cause of vasoconstriction in most serotonergic drugs. | |||
==Chemistry== | ==Chemistry== |