Serotonin: Difference between revisions

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Extremely high levels of serotonin can cause a condition known as serotonin syndrome that has toxic and potentially fatal effects. Serotonin syndrome, also known as serotonin toxicity, can be induced via overdose of particular drugs and some drug combinations. Many drug interactions have been found to cause serotonin syndrome, the most notorious of which being the combination of an SSRI antidepressant and an [[MAOI]] antidepressant.

Extremely high levels of serotonin can cause a condition known as serotonin syndrome that has toxic and potentially fatal effects. Serotonin syndrome, also known as serotonin toxicity, can be induced via overdose of particular drugs and some drug combinations where both substances have serenonergic actions. Many drug interactions have been found to cause serotonin syndrome, the most notorious of which being the combination of an SSRI antidepressant and an [[MAOI]] antidepressant.

Symptoms can start showing within minutes and can include increased heart rate, sweating, anxiety, hyperthermia, shivering, high blood pressure, agitation, seizures, and rarely death. Symptoms usually resolve after 24 hours, but can last up to several months in some cases.

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 {{main|Serotonin syndrome}}
-Extremely high levels of serotonin can cause a condition known as serotonin syndrome that has toxic and potentially fatal effects. Serotonin syndrome, also known as serotonin toxicity, can be induced via overdose of particular drugs and some drug combinations. Many drug interactions have been found to cause serotonin syndrome, the most notorious of which being the combination of an SSRI antidepressant and an [[MAOI]] antidepressant.
+Extremely high levels of serotonin can cause a condition known as serotonin syndrome that has toxic and potentially fatal effects. Serotonin syndrome, also known as serotonin toxicity, can be induced via overdose of particular drugs and some drug combinations where both substances have serenonergic actions. Many drug interactions have been found to cause serotonin syndrome, the most notorious of which being the combination of an SSRI antidepressant and an [[MAOI]] antidepressant.
 Symptoms can start showing within minutes and can include increased heart rate, sweating, anxiety, hyperthermia, shivering, high blood pressure, agitation, seizures, and rarely death. Symptoms usually resolve after 24 hours, but can last up to several months in some cases.