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4-AcO-MET: Difference between revisions
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*'''[[Effect::Auditory hallucinations|Hallucinations]]''' | *'''[[Effect::Auditory hallucinations|Hallucinations]]''' | ||
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===Experience reports=== | ===Experience reports=== | ||
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==Toxicity and harm potential== | ==Toxicity and harm potential== | ||
{{further|Research chemicals#Toxicity and harm potential|Responsible use #Hallucinogens}} | {{further|Research chemicals#Toxicity and harm potential|Responsible use #Hallucinogens}} | ||
The toxicity and long-term health effects of recreational 4-AcO-MET use do not seem to have been studied in any scientific context and the exact [[Toxicity::toxic dose is unknown]]. This is because 4-AcO-MET is a [[research chemical]] with very little history of human usage. Anecdotal evidence | The toxicity and long-term health effects of recreational 4-AcO-MET use do not seem to have been studied in any scientific context and the exact [[Toxicity::toxic dose is unknown]]. This is because 4-AcO-MET is a [[research chemical]] with very little history of human usage. | ||
It is strongly recommended that one use [[responsible drug use|harm reduction practices]] when using this | |||
Anecdotal evidence suggests that there are no negative health effects attributed to simply trying the drug by itself at low to moderate doses and using it very sparingly (but nothing can be completely guaranteed). [https://www.google.com/ Independent research] should always be done to ensure that a combination of two or more substances is safe before consumption. | |||
It is strongly recommended that one use [[responsible drug use|harm reduction practices]] when using this substance. | |||
===Tolerance and addiction potential=== | ===Tolerance and addiction potential=== | ||
4-AcO-MET is [[Addiction potential::not habit-forming]] and the desire to use it can actually decrease with use. It is most often self-regulating. | 4-AcO-MET is [[Addiction potential::not habit-forming]] and the desire to use it can actually decrease with use. It is most often self-regulating. | ||
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Tolerance to the effects of 4-AcO-MET are built [[Time to full tolerance::almost immediately after ingestion]]. After that, it takes about [[Time to half tolerance::3 days]] for the tolerance to be reduced to half and [[Time to zero tolerance::7 days]] to be back at baseline (in the absence of further consumption). 4-AcO-MET presents cross-tolerance with [[Cross-tolerance::all [[psychedelic]]s]], meaning that after the consumption of 4-AcO-MET all psychedelics will have a reduced effect. | Tolerance to the effects of 4-AcO-MET are built [[Time to full tolerance::almost immediately after ingestion]]. After that, it takes about [[Time to half tolerance::3 days]] for the tolerance to be reduced to half and [[Time to zero tolerance::7 days]] to be back at baseline (in the absence of further consumption). 4-AcO-MET presents cross-tolerance with [[Cross-tolerance::all [[psychedelic]]s]], meaning that after the consumption of 4-AcO-MET all psychedelics will have a reduced effect. | ||
==Legal | ===Dangerous interactions=== | ||
{{DangerousInteractions/Intro}} | |||
*'''[https://en.wikipedia.org/wiki/Lithium_(medication) Lithium]''' - Lithium is often used as treatment for bipolar disorder. It can amplify the intensity of psychedelics to dangerous levels and has been strongly linked with psychosis and seizures. The causes are poorly understood, but it may be due to its [[Glutamate|glutaminergic]] and [[GABA|GABAergic]] properties.{{citation needed}} | |||
*'''[[Stimulants]]''' - Stimulants affect many parts of the brain. Combined with psychedelics, stimulation can turn into uncontrollable [[anxiety]], [[paranoia]], [[thought loops]] and [[panic attacks]]. This interaction may cause elevated risk of psychosis.{{citation needed}} | |||
*'''[[Tramadol]]''' - Tramadol lowers the seizure threshold<ref>Talaie, H., Panahandeh, R., Fayaznouri, M. R., Asadi, Z., & Abdollahi, M. (2009). Dose-independent occurrence of seizure with tramadol. Journal of Medical Toxicology, 5(2), 63-67. doi:10.1007/BF03161089</ref> and [[psychedelics]] may act as triggers for seizures, particularly in those who are predisposed to them.{{citation needed}} | |||
==Legal status== | |||
{{legalStub}} | {{legalStub}} | ||
*'''United States''' - 4-AcO-MET is unscheduled in the United States. It may be considered an analogue of [[psilocin]] (''4-HO-DMT'') which is a Schedule I drug under the Controlled Substances Act. As such, the sale for human consumption or the use for illicit non-medical or industrial intents and purposes could be prosecuted as crimes under the Federal Analogue Act.{{citation needed}} | *'''United States''' - 4-AcO-MET is unscheduled in the United States. It may be considered an analogue of [[psilocin]] (''4-HO-DMT'') which is a Schedule I drug under the Controlled Substances Act. As such, the sale for human consumption or the use for illicit non-medical or industrial intents and purposes could be prosecuted as crimes under the Federal Analogue Act.{{citation needed}} | ||
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==See also== | ==See also== | ||
*[[Responsible use]] | *[[Responsible use]] | ||
*[[ | *[[Research chemical]] | ||
*[[Psychedelic]] | *[[Psychedelic]] | ||
*[[Tryptamine]] | *[[Tryptamine]] | ||
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*[https://en.wikipedia.org/wiki/4-Acetoxy-MET 4-AcO-MET (Wikipedia)] | *[https://en.wikipedia.org/wiki/4-Acetoxy-MET 4-AcO-MET (Wikipedia)] | ||
*[https://isomerdesign.com/PiHKAL/explore.php?id=5532 4-AcO-MET (Isomer Design)] | *[https://isomerdesign.com/PiHKAL/explore.php?id=5532 4-AcO-MET (Isomer Design)] | ||
*[http://www.bluelight.org/vb/threads/403781-The-Big-amp-Dandy-4-AcO-MET-Thread 4-AcO-MET (Bluelight)] | ===Discussion=== | ||
*[http://www.bluelight.org/vb/threads/403781-The-Big-amp-Dandy-4-AcO-MET-Thread The Big & Dandy 4-AcO-MET Thread (Bluelight)] | |||
==References== | ==References== | ||