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Opioids: Difference between revisions
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===Receptor types=== | ===Receptor types=== | ||
Opioids act on the three main classes of | Opioids act on the three main classes of opioid receptor in the nervous system, μ, κ, δ (mu, kappa, and delta).<ref name="receptors">Opioid - Chapter 2: The Endogeneous Opioid Systems | ||
(http://www.stoppain.org / Beth Israel Medical Center's Department of Pain Medicine and Palliative Care) | https://web.archive.org/web/20110719072413/http://www.stoppain.org/pcd/_pdf/OpioidChapter2.pdf</ref> Each opioid is measured by its [[agonist]]ic or [[antagonist]]ic effects towards the receptors, with the responses to the different receptor sub-types (e.g., μ1 and μ2) providing even more effects. Opioid receptors are found mainly within the brain, but also within the spinal cord and digestive tract.<ref>Opioid receptors in the gastrointestinal tract | (http://www.stoppain.org / Beth Israel Medical Center's Department of Pain Medicine and Palliative Care) | https://web.archive.org/web/20110719072413/http://www.stoppain.org/pcd/_pdf/OpioidChapter2.pdf</ref> Each opioid is measured by its [[agonist]]ic or [[antagonist]]ic effects towards the receptors, with the responses to the different receptor sub-types (e.g., μ1 and μ2) providing even more effects. Opioid receptors are found mainly within the brain, but also within the spinal cord and digestive tract.<ref>Opioid receptors in the gastrointestinal tract | ||
(PubMed.gov / NCBI) | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3163293</ref> | (PubMed.gov / NCBI) | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3163293</ref> | ||