6-APB: Difference between revisions
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'''6-(2-Aminopropyl)benzofuran''' (also known as '''6-APB''' or by the brand-name '''Benzofury''') is a novel [[psychoactive class::entactogen]] substance of the [[chemical class::benzofuran]] class | '''6-(2-Aminopropyl)benzofuran''' (also known as '''6-APB''' or by the brand-name '''Benzofury''') is a novel [[psychoactive class::entactogen]] substance of the [[chemical class::benzofuran]] class. It produces long-lived [[entactogenic]] and [[stimulant]] effects such as [[Anxiety suppression|anxiety suppression]], [[disinhibition]], [[Muscle relaxation|muscle relaxation]], and [[euphoria]] when [[Routes of administration|administered]]. It is structurally related to entactogens like [[MDA]], [[MDMA]], [[5-APB]], and [[5-MAPB]]. | ||
6-APB was first synthesized in 1993 by psychedelic chemist and researcher [[David E. Nichols]] as a potential non-neurotoxic alternative to [[MDMA]].<ref name="Nichols">Monte, A. P., Marona-Lewicka, D., Cozzi, N. V., & Nichols, D. E. (1993). Synthesis and pharmacological examination of benzofuran, indan, and tetralin analogs of 3, 4-(methylenedioxy) amphetamine. Journal of Medicinal Chemistry, 36(23), 3700-3706. https://doi.org/10.1021/jm00075a027</ref> However, it did not come into popular recreational use until over a decade later, where it briefly entered the rave scene and global research chemicals market. It was sold along with other novel benzofuran entactogens under the name "Benzofury" before its sale and import were subsequently banned.{{citation needed}} | 6-APB was first synthesized in 1993 by psychedelic chemist and researcher [[David E. Nichols]] as a potential non-neurotoxic alternative to [[MDMA]].<ref name="Nichols">Monte, A. P., Marona-Lewicka, D., Cozzi, N. V., & Nichols, D. E. (1993). Synthesis and pharmacological examination of benzofuran, indan, and tetralin analogs of 3, 4-(methylenedioxy) amphetamine. Journal of Medicinal Chemistry, 36(23), 3700-3706. https://doi.org/10.1021/jm00075a027</ref> However, it did not come into popular recreational use until over a decade later, where it briefly entered the rave scene and global research chemicals market. It was sold along with other novel benzofuran entactogens under the name "Benzofury" before its sale and import were subsequently banned.{{citation needed}} |