5-MeO-MiPT: Difference between revisions

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'''5-Methoxy-N-methyl-N-isopropyltryptamine''' (also known as '''5-MeO-MiPT''' or colloquially as '''Moxy''') is a [[psychoactive class::psychedelic]] substance of the [[chemical class::tryptamine]] class that produces [[psychedelic]] effects when [[administered]]. Its effects are commonly reported to be stimulating and ~~physically-oriented~~, lacking in significant visual distortions. It is a structural analog of [[MiPT]], [[4-HO-MiPT]], and [[5-MeO-DiPT]].

'''5-Methoxy-N-methyl-N-isopropyltryptamine''' (also known as '''5-MeO-MiPT''' or colloquially as '''Moxy''') is a [[psychoactive class::psychedelic]] substance of the [[chemical class::tryptamine]] class that produces [[psychedelic]] effects when [[administered]]. Its effects are commonly reported to be stimulating and mildly entactogenic, lacking in significant visual distortions. It is a structural analog of [[MiPT]], [[4-HO-MiPT]], and [[5-MeO-DiPT]].

5-MeO-MiPT has no history of human usage prior to the 1985 publication of its synthesis and pharmacology by Repke, Grotjahn & Shulgin.{{citation needed}}

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5-MeO-MiPT's [[psychedelic]] effects are believed to come from its efficacy at the [[Serotonin#The 5-HT system|5-HT<sub>2A</sub> receptor]] as a [[Agonist#Agonists|partial agonist]]<ref>The effects of non-medically used psychoactive drugs on monoamine neurotransmission in rat brain (ScienceDirect) | http://www.sciencedirect.com/science/article/pii/S0014299906013811</ref><ref>Psychotomimetic N-methyl-N-isopropyltryptamines. Effects of variation of aromatic oxygen substituents | http://pubs.acs.org/doi/abs/10.1021/jm00145a007</ref> and additional mechanisms of action such as the inhibition of [[MAOI|MAO]] (i.e. digestive enzymes in the stomach) have also been speculated upon, though this has yet to be demonstrated scientifically.

~~==Routes of administration==~~

This substance can be taken via oral ingestion or it can be smoked. When ingested orally the experience puts more of an emphasis on visual effects but can be broken up into two stages; the first half of the trip feels [[stimulant|stimulating]] and [[entactogens|entactogenic]] whilst the second half feels more similar to a traditional [[tryptamine]] [[psychedelic]].

If smoked however these stages of experience are not present and the experience places more of an emphasis on physically and cognitively stimulating effects accompanied by subtle and mild changes in visual perception.

==Subjective effects==

This substance can be taken via oral ingestion or it can be smoked. When ingested orally the experience puts more of an emphasis on visual effects but can be broken up into two stages; the first half of the experience feels [[stimulant|stimulating]] and [[entactogens|entactogenic]] whilst the second half feels more similar to a traditional [[tryptamine]] [[psychedelic]]. When smoked, the physically and cognitively stimulating effects become emphasized.

{{effects/base

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 {{SubstanceBox/5-MeO-MiPT}}
-'''5-Methoxy-N-methyl-N-isopropyltryptamine''' (also known as '''5-MeO-MiPT''' or colloquially as '''Moxy''') is a [[psychoactive class::psychedelic]] substance of the [[chemical class::tryptamine]] class that produces [[psychedelic]] effects when [[administered]]. Its effects are commonly reported to be stimulating and physically-oriented, lacking in significant visual distortions. It is a structural analog of [[MiPT]], [[4-HO-MiPT]], and [[5-MeO-DiPT]].
+'''5-Methoxy-N-methyl-N-isopropyltryptamine''' (also known as '''5-MeO-MiPT''' or colloquially as '''Moxy''') is a [[psychoactive class::psychedelic]] substance of the [[chemical class::tryptamine]] class that produces [[psychedelic]] effects when [[administered]]. Its effects are commonly reported to be stimulating and mildly entactogenic, lacking in significant visual distortions. It is a structural analog of [[MiPT]], [[4-HO-MiPT]], and [[5-MeO-DiPT]].
 -MeO-MiPT has no history of human usage prior to the 1985 publication of its synthesis and pharmacology by Repke, Grotjahn & Shulgin.{{citation needed}}
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 {{Further|Serotonergic psychedelic}}
 -MeO-MiPT's [[psychedelic]] effects are believed to come from its efficacy at the [[Serotonin#The 5-HT system|5-HT<sub>2A</sub> receptor]] as a [[Agonist#Agonists|partial agonist]]<ref>The effects of non-medically used psychoactive drugs on monoamine neurotransmission in rat brain (ScienceDirect) | http://www.sciencedirect.com/science/article/pii/S0014299906013811</ref><ref>Psychotomimetic N-methyl-N-isopropyltryptamines. Effects of variation of aromatic oxygen substituents | http://pubs.acs.org/doi/abs/10.1021/jm00145a007</ref> and additional mechanisms of action such as the inhibition of [[MAOI|MAO]] (i.e. digestive enzymes in the stomach) have also been speculated upon, though this has yet to be demonstrated scientifically.
-==Routes of administration==
-This substance can be taken via oral ingestion or it can be smoked. When ingested orally the experience puts more of an emphasis on visual effects but can be broken up into two stages; the first half of the trip feels [[stimulant|stimulating]] and [[entactogens|entactogenic]] whilst the second half feels more similar to a traditional [[tryptamine]] [[psychedelic]].
-If smoked however these stages of experience are not present and the experience places more of an emphasis on physically and cognitively stimulating effects accompanied by subtle and mild changes in visual perception.
 ==Subjective effects==
+This substance can be taken via oral ingestion or it can be smoked. When ingested orally the experience puts more of an emphasis on visual effects but can be broken up into two stages; the first half of the experience feels [[stimulant|stimulating]] and [[entactogens|entactogenic]] whilst the second half feels more similar to a traditional [[tryptamine]] [[psychedelic]]. When smoked, the physically and cognitively stimulating effects become emphasized.
 {{Preamble/SubjectiveEffects}}
 {{effects/base