3-MeO-PCE: Difference between revisions

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'''3-Methoxyeticyclidine''' (also known as '''Methoxieticyclidine''' and '''3-MeO-PCE''') is a novel ~~synthetic~~ [[Psychoactive class::dissociative]] substance of the [[Chemical class::arylcyclohexylamine]] ~~chemical~~ class that produces [[dissociative~~]], [[stimulating~~]] and [[hallucinogenic]] effects when [[Routes of administration|administered]].

'''3-Methoxyeticyclidine''' (also known as '''Methoxieticyclidine''' and '''3-MeO-PCE''') is a novel [[Psychoactive class::dissociative]] substance of the [[Chemical class::arylcyclohexylamine]] class that produces [[dissociative]] and [[hallucinogenic]] effects when [[Routes of administration|administered]]. It is a structural analog of [[PCE]].

~~Early reports indicate that 3-MeO-PCE shares extremely similar properties to that~~ of ~~[[3-MeO-PCP]] and to a lesser extent, [[PCP]]/~~[[PCE]], [[MXE]] and [[O-PCE]]<ref>From PCP to MXE: a comprehensive review of the non-medical use of dissociative drugs | http://onlinelibrary.wiley.com/doi/10.1002/dta.1620/abstract</ref>, but with what seems to be a moderately higher risk of inducing states of [[delusions]], [[mania]] and [[psychosis]]. Because of this, it is highly recommended to use [[responsible drug use]] practices when using this substance such as using a [[milligram scale]] (and preferably [[volumetric liquid dosing]]) as well as having a sober [[trip sitter]] present throughout the experience.

3-MeO-PCE began to gain popularity in 2010 <ref>3-MeO-PCE - Explore - Google Trends | https://www.google.com/trends/explore?date=all&q=3-MeO-PCE</ref> and is sold on the online grey area [[research chemical]] market as a legal alternative to [[PCP]] or [[ketamine]].<ref>Syntheses and analytical characterizations of N-alkyl-arylcyclohexylamines. | https://www.ncbi.nlm.nih.gov/pubmed/26360516</ref><ref>From the Street to the Laboratory: Analytical Profiles of Methoxetamine, 3-Methoxyeticyclidine and 3-Methoxyphencyclidine and their Determination in Three Biological Matrices

| http://jat.oxfordjournals.org/content/37/5/277.full</ref><ref>http://nsddb.eu/substance/296/</ref>

Very little data exists about the pharmacological properties, metabolism, and toxicity of DCK, and it has a very brief history of human usage. It is strongly recommended that one use harm reduction practices if using this substance.

==Chemistry==

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 {{SubstanceBox/3-MeO-PCE}}
-'''3-Methoxyeticyclidine''' (also known as '''Methoxieticyclidine''' and '''3-MeO-PCE''') is a novel synthetic [[Psychoactive class::dissociative]] substance of the [[Chemical class::arylcyclohexylamine]] chemical class that produces [[dissociative]], [[stimulating]] and [[hallucinogenic]] effects  when [[Routes of administration|administered]].
+'''3-Methoxyeticyclidine''' (also known as '''Methoxieticyclidine''' and '''3-MeO-PCE''') is a novel [[Psychoactive class::dissociative]] substance of the [[Chemical class::arylcyclohexylamine]] class that produces [[dissociative]] and [[hallucinogenic]] effects when [[Routes of administration|administered]]. It is a structural analog of [[PCE]].
-Early reports indicate that 3-MeO-PCE shares extremely similar properties to that of [[3-MeO-PCP]] and to a lesser extent, [[PCP]]/[[PCE]], [[MXE]] and [[O-PCE]]<ref>From PCP to MXE: a comprehensive review of the non-medical use of dissociative drugs | http://onlinelibrary.wiley.com/doi/10.1002/dta.1620/abstract</ref>, but with what seems to be a moderately higher risk of inducing states of [[delusions]], [[mania]] and [[psychosis]]. Because of this, it is highly recommended to use [[responsible drug use]] practices when using this substance such as using a [[milligram scale]] (and preferably [[volumetric liquid dosing]]) as well as having a sober [[trip sitter]] present throughout the experience.
 -MeO-PCE began to gain popularity in 2010 <ref>3-MeO-PCE - Explore - Google Trends | https://www.google.com/trends/explore?date=all&q=3-MeO-PCE</ref> and is sold on the online grey area [[research chemical]] market as a legal alternative to [[PCP]] or [[ketamine]].<ref>Syntheses and analytical characterizations of N-alkyl-arylcyclohexylamines. | https://www.ncbi.nlm.nih.gov/pubmed/26360516</ref><ref>From the Street to the Laboratory: Analytical Profiles of Methoxetamine, 3-Methoxyeticyclidine and 3-Methoxyphencyclidine and their Determination in Three Biological Matrices
   | http://jat.oxfordjournals.org/content/37/5/277.full</ref><ref>http://nsddb.eu/substance/296/</ref>
+Very little data exists about the pharmacological properties, metabolism, and toxicity of DCK, and it has a very brief history of human usage. It is strongly recommended that one use harm reduction practices if using this substance.
 ==Chemistry==