Prochlorperazine: Difference between revisions

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==Toxicity and harm potential==

Nervous system side effects have been associated with the use of prochlorperazine. [http://en.wikipedia.org/wiki/Extrapyramidal_symptoms Extrapyramidal side effects] such as acute [http://en.wikipedia.org/wiki/Dystonia dystonic] reactions, [http://en.wikipedia.org/wiki/Parkinsonism ~~parkinsonism~~] (not to be confused with Parkinson's disease), or akathisia can affect 2% of patients at low doses, whereas higher doses may affect as many as 40% of patients.<ref>Psychiatric Side Effects of Prescription and Over-the-counter Medications | http://books.google.com.au/books?id=K7kevbILCuQC&source=gbs_navlinks_s</ref><ref>http://www.drugs.com/sfx/procot-side-effects.html</ref>

Nervous system side effects have been associated with the use of prochlorperazine. [http://en.wikipedia.org/wiki/Extrapyramidal_symptoms Extrapyramidal side effects] such as acute [http://en.wikipedia.org/wiki/Dystonia dystonic] reactions, [http://en.wikipedia.org/wiki/Parkinsonism pseudoparkinsonism] (not to be confused with Parkinson's disease), or akathisia can affect 2% of patients at low doses, whereas higher doses may affect as many as 40% of patients.<ref>Psychiatric Side Effects of Prescription and Over-the-counter Medications | http://books.google.com.au/books?id=K7kevbILCuQC&source=gbs_navlinks_s</ref><ref>http://www.drugs.com/sfx/procot-side-effects.html</ref>

Prochlorperazine can also cause a life-threatening condition called neuroleptic malignant syndrome (NMS). Some symptoms of NMS include a high fever, stiff muscles, confusion, irregular pulse or blood pressure, a fast heart rate (tachycardia), sweating, or irregular heart rhythms (arrhythmias).

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 ==Toxicity and harm potential==
-Nervous system side effects have been associated with the use of prochlorperazine. [http://en.wikipedia.org/wiki/Extrapyramidal_symptoms Extrapyramidal side effects] such as acute [http://en.wikipedia.org/wiki/Dystonia dystonic] reactions, [http://en.wikipedia.org/wiki/Parkinsonism parkinsonism] (not to be confused with Parkinson's disease), or akathisia can affect 2% of patients at low doses, whereas higher doses may affect as many as 40% of patients.<ref>Psychiatric Side Effects of Prescription and Over-the-counter Medications | http://books.google.com.au/books?id=K7kevbILCuQC&source=gbs_navlinks_s</ref><ref>http://www.drugs.com/sfx/procot-side-effects.html</ref>
+Nervous system side effects have been associated with the use of prochlorperazine. [http://en.wikipedia.org/wiki/Extrapyramidal_symptoms Extrapyramidal side effects] such as acute [http://en.wikipedia.org/wiki/Dystonia dystonic] reactions, [http://en.wikipedia.org/wiki/Parkinsonism pseudoparkinsonism] (not to be confused with Parkinson's disease), or akathisia can affect 2% of patients at low doses, whereas higher doses may affect as many as 40% of patients.<ref>Psychiatric Side Effects of Prescription and Over-the-counter Medications | http://books.google.com.au/books?id=K7kevbILCuQC&source=gbs_navlinks_s</ref><ref>http://www.drugs.com/sfx/procot-side-effects.html</ref>
 Prochlorperazine can also cause a life-threatening condition called neuroleptic malignant syndrome (NMS). Some symptoms of NMS include a high fever, stiff muscles, confusion, irregular pulse or blood pressure, a fast heart rate (tachycardia), sweating, or irregular heart rhythms (arrhythmias).