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5-MeO-DiBF: Difference between revisions
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==Pharmacology== | ==Pharmacology== | ||
{{Further|Serotonergic psychedelic}} | {{Further|Serotonergic psychedelic}} | ||
5-MeO-DiBF likely acts as a [[Serotonin#The_5-HT_system|5-HT<sub>2A</sub>]] [[Agonist#Agonists|partial agonist]]. The [[psychedelic]] effects are believed to come from its efficacy at the 5-HT<sub>1A</sub> and 5-HT2 family of serotonin receptors. However, the role of these interactions and how they result in the psychedelic experience | 5-MeO-DiBF likely acts as a [[Serotonin#The_5-HT_system|5-HT<sub>2A</sub>]] [[Agonist#Agonists|partial agonist]]. The [[psychedelic]] effects are believed to come from its efficacy at the 5-HT<sub>1A</sub> and 5-HT2 family of serotonin receptors. However, the role of these interactions and how they result in the psychedelic experience continues to remain elusive. | ||
This compound is several times less potent as a serotonin agonist than 5-MeO-DiPT. It has relatively more activity at 5-HT1A, but still shows strongest effects at the 5-HT2 family of receptors.<ref>Benzofuran bioisosteres of hallucinogenic tryptamines (PubMed.gov / NCBI) | https://www.ncbi.nlm.nih.gov/pubmed/1534585</ref><ref>Differential interactions of indolealkylamines with 5-hydroxytryptamine receptor subtypes (PubMed.gov / NCBI) | https://www.ncbi.nlm.nih.gov/pubmed/2139186</ref> | This compound is several times less potent as a serotonin agonist than 5-MeO-DiPT. It has relatively more activity at 5-HT1A, but still shows strongest effects at the 5-HT2 family of receptors.<ref>Benzofuran bioisosteres of hallucinogenic tryptamines (PubMed.gov / NCBI) | https://www.ncbi.nlm.nih.gov/pubmed/1534585</ref><ref>Differential interactions of indolealkylamines with 5-hydroxytryptamine receptor subtypes (PubMed.gov / NCBI) | https://www.ncbi.nlm.nih.gov/pubmed/2139186</ref> | ||