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Clonidine: Difference between revisions
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*'''[[Depressants]]''' (''[[1,4-Butanediol]], [[2M2B]], [[alcohol]],<ref>Koski, A., Ojanperä, I., & Vuori, E. (2002). Alcohol and benzodiazepines in fatal poisonings. Alcoholism: Clinical and Experimental Research, 26(7), 956-959.</ref> [[benzodiazepines]], [[barbiturates]], [[GHB]]/[[GBL]], [[methaqualone]], [[opioids]]'') - This combination can result in dangerous or even fatal levels of [[respiratory depression]]. These substances potentiate the [[muscle relaxation]], [[sedation]] and [[amnesia]] caused by one another and can lead to unexpected loss of consciousness at high doses. There is also an increased risk of vomiting during unconsciousness and death from the resulting suffocation. If this occurs, users should attempt to fall asleep in the [[recovery position]] or have a friend move them into it. | *'''[[Depressants]]''' (''[[1,4-Butanediol]], [[2M2B]], [[alcohol]],<ref>Koski, A., Ojanperä, I., & Vuori, E. (2002). Alcohol and benzodiazepines in fatal poisonings. Alcoholism: Clinical and Experimental Research, 26(7), 956-959.</ref> [[benzodiazepines]], [[barbiturates]], [[GHB]]/[[GBL]], [[methaqualone]], [[opioids]]'') - This combination can result in dangerous or even fatal levels of [[respiratory depression]]. These substances potentiate the [[muscle relaxation]], [[sedation]] and [[amnesia]] caused by one another and can lead to unexpected loss of consciousness at high doses. There is also an increased risk of vomiting during unconsciousness and death from the resulting suffocation. If this occurs, users should attempt to fall asleep in the [[recovery position]] or have a friend move them into it. | ||
*'''[[Stimulants]]''' (''[[Lisdexamfetamine]], [[amphetamine]], [[propylhexedrine]], others'') - This combination could potentially increase the chance of an abnormal heartbeat.{{citation needed}} Caution should be exercised and physical activity should be avoided. However, in clinical use, this combination has a positive effect on the ''mind'', especially in ADHD, and can be used for focusing or memory retention. Still, it is not wise to combine high doses of each substance.<ref>Revisiting clonidine: an innovative add-on option for attention-deficit/hyperactivity disorder. Childress AC, Sallee FR. (2012) https://www.ncbi.nlm.nih.gov/pubmed/22462040</ref> | *'''[[Stimulants]]''' (''[[Lisdexamfetamine]], [[amphetamine]], [[propylhexedrine]], [[methylphenidate]], others'') - This combination could potentially increase the chance of an abnormal heartbeat.{{citation needed}} Caution should be exercised and physical activity should be avoided. However, in clinical use, this combination has a positive effect on the ''mind'', especially in ADHD, and can be used for focusing or memory retention. Still, it is not wise to combine high doses of each substance.<ref>Revisiting clonidine: an innovative add-on option for attention-deficit/hyperactivity disorder. Childress AC, Sallee FR. (2012) https://www.ncbi.nlm.nih.gov/pubmed/22462040</ref> | ||
==Legality== | ==Legality== | ||
{{LegalStub}} | {{LegalStub}} | ||