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Clonidine: Difference between revisions
>Unity Use dangerous interactions template. Remove superfluous or prescriptive statements. Grammatics. |
>Sir Kibs Added descriptions to effects as well as citations for them. |
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*'''[[Effect::Sedation]]''' - Clonidine can be strong in its sedating effect. This can lead to atypical walking gait from decreased locomotion coordination. | *'''[[Effect::Sedation]]''' - Clonidine can be strong in its sedating effect. This can lead to atypical walking gait from decreased locomotion coordination. | ||
*'''[[Effect::Decreased heart rate]]''' | *'''[[Effect::Decreased heart rate]]''' | ||
*'''[[Effect::Decreased blood pressure]]''' | *'''[[Effect::Decreased blood pressure]]''' - Clonidine's sympatholytic effects lower blood pressure and is commonly used to treat hypertension.<ref>Mitchell A, Bührmann S, Opazo Saez A, Rushentsova U, Schäfers RF, Philipp T, et al. Clonidine lowers blood pressure by reducing vascular resistance and cardiac output in young, healthy males. Cardiovasc Drugs Ther 2005;19:49–55. pmid:15883756</ref> | ||
*'''[[Effect::Abnormal heartbeat]]''' - Clonidine's chance of causing this is relatively low, but caution ''should'' be taken if clonidine is taken with other drugs that can cause this. Intense physical activity should probably be avoided. | *'''[[Effect::Abnormal heartbeat]]''' - Clonidine's chance of causing this is relatively low, but caution ''should'' be taken if clonidine is taken with other drugs that can cause this. Intense physical activity should probably be avoided. | ||
*'''[[Effect::Dry mouth]]''' | *'''[[Effect::Dry mouth]]''' | ||
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|{{effects/cognitive| | |{{effects/cognitive| | ||
*'''[[Effect::Cognitive fatigue]]''' | *'''[[Effect::Cognitive fatigue]]''' | ||
*'''[[Effect::Anxiety suppression]]''' - Clonidine has relatively strong anxiolytic effects and is sometimes used clinically to treat anxiety.<ref>Hoehn-Saric R, Merchant AF, Keyser ML, Smith NVK. Effects of Clonidine on Anxiety Disorders. Arch Gen Psychiatry.</ref> | |||
*'''[[Effect::Irritability]]''' | *'''[[Effect::Irritability]]''' | ||
*'''[[Effect::Focus suppression]]''' - This usually occurs at higher doses. The effect is also usually from the sedated state. | *'''[[Effect::Focus suppression]]''' - This usually occurs at higher doses. The effect is also usually from the sedated state. | ||
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}} | }} | ||
}} | }} | ||
==Toxicity and harm potential== | ==Toxicity and harm potential== | ||
It is strongly recommended that one use [[responsible use|harm reduction practices]] when using this drug, especially concurrently with other [[depressants]]. According to drugs.com, clonidine's maximum medical dose for hypotension is 2.4 miligrams in divided doses. | It is strongly recommended that one use [[responsible use|harm reduction practices]] when using this drug, especially concurrently with other [[depressants]]. According to drugs.com, clonidine's maximum medical dose for hypotension is 2.4 miligrams in divided doses. | ||