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2C-C: Difference between revisions
>Niamh Summary - clarified date and authorship of initial published synthesis |
>Unity SummarySheet, Intro restyling. Grammatics. Legal issues -> Legality. |
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{{SubstanceBox/2C-C}} | {{SubstanceBox/2C-C}} | ||
'''2,5-Dimethoxy-4-chlorophenethylamine''' (also known as '''2C-C''') is a synthetic [[Psychoactive class::psychedelic]] substance of the [[Chemical class::phenethylamine]] chemical class and [[2C-x family]] that produces phenethylamine-type [[psychedelic]] effects when [[routes of administration|administered]].<ref>Alexander Shulgin - PIHKAL | http://www.erowid.org/library/books_online/pihkal/pihkal033.shtml</ref> | |||
Many users report that 2C-C | 2C-C was first synthesized by Alice C. Cheng and Neal Castagnoli Jr. in 1983 as an intermediate in a study evaluating the neurotoxicity of 6-hydroxydopamine analogs <ref>Synthesis and physicochemical and neurotoxicity studies of 1-(4-substituted-2,5-dihydroxyphenyl)-2-aminoethane analogs of 6-hydroxydopamine. Alice C. Cheng and Neal Castagnoli Jr. Journal of Medicinal Chemistry 1984 27 (4), 513-520; DOI: 10.1021/jm00370a014 (acs.org) | http://pubs.acs.org/doi/abs/10.1021/jm00370a014</ref> and later investigated and described by [[Alexander Shulgin]] in his book [[PiHKAL]] ("Phenethylamines I Have Known and Loved"). | ||
Many users report that the effects of 2C-C are gentler, more relaxed, and [[Sedation|sedating]] than other closely related [[psychedelic]] [[phenethylamines]] such as [[2C-B]], [[2C-I]], and [[2C-E]]. | |||
Today, it is used as a [[recreational drug use|recreational drug]] and [[entheogen]], is rarely sold on the streets and almost exclusively obtained as a grey area [[research chemical]] via online vendors. It is relatively uncommon and has only a short history of human use. | |||
==Chemistry== | ==Chemistry== | ||
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==Toxicity and harm potential== | ==Toxicity and harm potential== | ||
{{further|Research chemicals#Toxicity and harm potential|Responsible use #Hallucinogens}} | {{further|Research chemicals#Toxicity and harm potential|Responsible use #Hallucinogens}} | ||
The toxicity and long-term health effects of recreational 2C-C use do not seem to have been studied in any scientific context and the exact toxic dosage is unknown. Anecdotal evidence from people who have tried 2C-C within the | The toxicity and long-term health effects of recreational 2C-C use do not seem to have been studied in any scientific context and the exact toxic dosage is unknown. Anecdotal evidence from people who have tried 2C-C within the community suggests that there are [[Toxicity::no negative health effects attributed to trying this substance]], but nothing can be completely guaranteed. | ||
It is strongly recommended that one use [[responsible drug use|harm reduction practices]] when using this substance. | |||
===Tolerance and addiction potential=== | ===Tolerance and addiction potential=== | ||
2C-C is [[Addiction potential::not habit-forming]] and the desire to use it can actually decrease with use. It is most often self-regulating. | 2C-C is [[Addiction potential::not habit-forming]] and the desire to use it can actually decrease with use. It is most often self-regulating. | ||
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Tolerance to the effects of 2C-C are built [[Time to full tolerance::almost immediately after ingestion]]. After that, it takes about [[Time to half tolerance::3 days]] for the tolerance to be reduced to half and [[Time to zero tolerance::7 days]] to be back at baseline (in the absence of further consumption). 2C-C presents cross-tolerance with [[Cross-tolerance::all [[psychedelic]]s]], meaning that after the consumption of 2C-C all psychedelics will have a reduced effect. | Tolerance to the effects of 2C-C are built [[Time to full tolerance::almost immediately after ingestion]]. After that, it takes about [[Time to half tolerance::3 days]] for the tolerance to be reduced to half and [[Time to zero tolerance::7 days]] to be back at baseline (in the absence of further consumption). 2C-C presents cross-tolerance with [[Cross-tolerance::all [[psychedelic]]s]], meaning that after the consumption of 2C-C all psychedelics will have a reduced effect. | ||
== | ==Legality== | ||
*'''Brazil''' - Possession, production and sale is illegal as it is listed on Portaria SVS/MS nº 344.<ref>http://portal.anvisa.gov.br/documents/10181/3115436/%281%29RDC_130_2016_.pdf/fc7ea407-3ff5-4fc1-bcfe-2f37504d28b7</ref> | *'''Brazil''' - Possession, production and sale is illegal as it is listed on Portaria SVS/MS nº 344.<ref>http://portal.anvisa.gov.br/documents/10181/3115436/%281%29RDC_130_2016_.pdf/fc7ea407-3ff5-4fc1-bcfe-2f37504d28b7</ref> | ||
*'''United States:''' 2C-C is listed in Schedule I of section 202(c) of the Controlled Substances Act in the United States. This was signed into law as of July 2012 under the Food and Drug Administration Safety and Innovation Act.<ref>S. 3187: Food and Drug Administration Safety and Innovation Act, Subtitle D-Synthetic Drugs | http://www.govtrack.us/congress/bills/112/s3187/text</ref> | *'''United States:''' 2C-C is listed in Schedule I of section 202(c) of the Controlled Substances Act in the United States. This was signed into law as of July 2012 under the Food and Drug Administration Safety and Innovation Act.<ref>S. 3187: Food and Drug Administration Safety and Innovation Act, Subtitle D-Synthetic Drugs | http://www.govtrack.us/congress/bills/112/s3187/text</ref> | ||