MDPV: Difference between revisions

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| ''[[MDPV/Summary|Summary sheet: MDPV]]''

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~~'''MDPV''' (~~'''3,4-Methylenedioxypyrovalerone'''; also known as '''~~Bath Salts~~''', ~~and~~ '''NRG-1''' among others) is a synthetic [[psychoactive class::stimulant]] ~~drug~~ of the [[substituted cathinone|cathinone]] and [[substituted pyrrolidine|pyrrolidine]] chemical classes. MDPV is thought to act primarily as as a [[norepinephrine]]-[[dopamine]] [[reuptake inhibitor]] (NDRI) and possesses powerful euphoric [[stimulant]] qualities. It was first developed in the 1960s by a team at Boehringer Ingelheim.<ref>US Patent 3478050 - 1-(3',4'-methylenedioxy-phenyl)-2-pyrrolidino-alkanones-(1) | https://www.google.com/patents/US3478050</ref>

'''3,4-Methylenedioxypyrovalerone''' (also known as '''MDPV''', '''NRG-1''', and imprecisely as '''Bath Salts''', among many others) is a novel, extremely potent synthetic [[psychoactive class::stimulant]] substance of the [[substituted cathinone|cathinone]] and [[substituted pyrrolidine|pyrrolidine]] chemical classes that produces states of extreme [[Euphoria|stimulant euphoria]], [[disinhibition]], and [[Increased libido|sexual arousal]] when [[Routes of administration|administered]]. MDPV is thought to act primarily as as a [[norepinephrine]]-[[dopamine]] [[reuptake inhibitor]] (NDRI) and possesses powerful euphoric [[stimulant]] qualities. It was first developed in the 1960s by a team at Boehringer Ingelheim.<ref>US Patent 3478050 - 1-(3',4'-methylenedioxy-phenyl)-2-pyrrolidino-alkanones-(1) | https://www.google.com/patents/US3478050</ref>

MDPV remained an obscure stimulant until around 2004, when it was reportedly first made available to the public as a [[designer drug]]. Products labeled as "bath salts" containing MDPV were previously sold as recreational drugs in gas stations and convenience stores in the United States, similar to the marketing strategy of [[Synthetic cannabinoids|Spice and K2]] as incense.

MDPV remained an obscure stimulant until around 2004, when it was reportedly first made available to the public as a [[designer drug]]. Products labeled as "bath salts" containing MDPV were previously sold as recreational drugs in gas stations and convenience stores in the United States, similar to the marketing strategy of [[Synthetic cannabinoids|Spice and K2]] as incense.{{citation needed}}

Historical reports show records of the preparation of MDPV for potential use as a CNS stimulant. It was claimed to have potential to be an alternative for racemic amphetamine and, although showing some desirable qualities such as reduced toxicity as compared to amphetamine, MDPV was chosen to not be developed as a medicinal drug.<ref> MDPV Summary | http://www.who.int/medicines/areas/quality_safety/4_13_Review.pdf?ua=1</ref>

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 | ''[[MDPV/Summary|Summary sheet: MDPV]]''
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-'''MDPV''' ('''3,4-Methylenedioxypyrovalerone'''; also known as '''Bath Salts''', and '''NRG-1''' among others) is a synthetic [[psychoactive class::stimulant]] drug of the [[substituted cathinone|cathinone]] and [[substituted pyrrolidine|pyrrolidine]] chemical classes. MDPV is thought to act primarily as as a [[norepinephrine]]-[[dopamine]] [[reuptake inhibitor]] (NDRI) and possesses powerful euphoric [[stimulant]] qualities. It was first developed in the 1960s by a team at Boehringer Ingelheim.<ref>US Patent 3478050 - 1-(3',4'-methylenedioxy-phenyl)-2-pyrrolidino-alkanones-(1) | https://www.google.com/patents/US3478050</ref>
+'''3,4-Methylenedioxypyrovalerone''' (also known as '''MDPV''', '''NRG-1''', and imprecisely as '''Bath Salts''', among many others) is a novel, extremely potent synthetic [[psychoactive class::stimulant]] substance of the [[substituted cathinone|cathinone]] and [[substituted pyrrolidine|pyrrolidine]] chemical classes that produces states of extreme [[Euphoria|stimulant euphoria]], [[disinhibition]], and [[Increased libido|sexual arousal]] when [[Routes of administration|administered]].  MDPV is thought to act primarily as as a [[norepinephrine]]-[[dopamine]] [[reuptake inhibitor]] (NDRI) and possesses powerful euphoric [[stimulant]] qualities. It was first developed in the 1960s by a team at Boehringer Ingelheim.<ref>US Patent 3478050 - 1-(3',4'-methylenedioxy-phenyl)-2-pyrrolidino-alkanones-(1) | https://www.google.com/patents/US3478050</ref>
-MDPV remained an obscure stimulant until around 2004, when it was reportedly first made available to the public as a [[designer drug]]. Products labeled as "bath salts" containing MDPV were previously sold as recreational drugs in gas stations and convenience stores in the United States, similar to the marketing strategy of [[Synthetic cannabinoids|Spice and K2]] as incense.
+MDPV remained an obscure stimulant until around 2004, when it was reportedly first made available to the public as a [[designer drug]]. Products labeled as "bath salts" containing MDPV were previously sold as recreational drugs in gas stations and convenience stores in the United States, similar to the marketing strategy of [[Synthetic cannabinoids|Spice and K2]] as incense.{{citation needed}}
 Historical reports show records of the preparation of MDPV for potential use as a CNS stimulant. It was claimed to have potential to be an alternative for racemic amphetamine and, although showing some desirable qualities such as reduced toxicity as compared to amphetamine, MDPV was chosen to not be developed as a medicinal drug.<ref> MDPV Summary | http://www.who.int/medicines/areas/quality_safety/4_13_Review.pdf?ua=1</ref>