5-APB: Difference between revisions

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| ''[[ 5-APB/Summary|Summary sheet: 5-APB]]''

|}

'''~~1-Benzofuran-~~5-~~ylpropan-~~2-~~amine~~''' (abbreviated '''5-APB''') is a [[Psychoactive class::entactogen]]~~ic substance~~ of the [[chemical class::~~phenethylamine~~]] and [[~~chemical class::benzofuran~~]] ~~classes~~.

'''5-(2-aminopropyl)benzofuran''' (abbreviated '''5-APB''') is a synthetic [[Psychoactive class::entactogen]] of the substituted [[chemical class::benzofuran]] class of chemicals, which are known to produce [[euphoria|euphoric]], [[entactogen]]ic, [[stimulant|stimulation]] and mildly [[hallucinogen]]ic effects. These include such [[MDA]]-inspired substances as [[5-APB]], [[6-APB]] and [[5-EAPB]], among others.

This compound is known for its [[stimulating]] and [[euphoria|euphoric]] effects which has resulted in its rise in popularity as a product which is easily accessible through the use of certain online [[research chemical]] vendors. It has been sold as a [[designer drug]] since 2010.<ref>EMCDDA–Europol 2010 Annual Report on the implementation of Council Decision 2005/387/JHA | http://www.emcdda.europa.eu/publications/implementation-reports/2010</ref>

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Anecdotal reports which describe the effects of this compound within our [[experience index]] include:

{{#ask: [[Category:5-APB]][[Category:Experience]]|format=ul|Columns=1}}

Additional experience reports can be found here:

* [https://www.erowid.org/experiences/subs/exp_5APB.shtml Erowid Experience Vaults: 5-APB]

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The toxicity and long-term health effects of recreational 5-APB use do not seem to have been studied in any scientific context and the [[Toxicity::exact toxic dosage is unknown]]. This is because 5-APB has very little history of human usage. Anecdotal evidence from people who have tried 5-APB within the community suggest that there do not seem to be any negative health effects attributed to simply trying this drug at low to moderate doses by itself and using it sparingly (but nothing can be completely guaranteed).

~~Its agonism~~ for 5-~~HT2B~~ makes it likely that 5-APB would be cardiotoxic with long-term use, as seen in other 5-HT2B agonists such as [[fenfluramine]] and [[MDMA]].

5-APB's high affinity for the 5-HT2b receptor makes it likely that 5-APB would be cardiotoxic with long-term use, as seen in other 5-HT2B agonists such as [[fenfluramine]] and [[MDMA]].

It is strongly recommended that one use [[responsible drug use|harm reduction practices]] when using this drug.

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*[[Responsible use]]

*[[Designer drug]]

*[[Psychedelics]]

*[[Entactogens]]

*[[Stimulants]]

*[[~~Phenethylamines~~]]

*[[5-MAPB]]

*[[6-APB]]

*[[MDA]]

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[[Category:Psychoactive substance]]

[[Category:Research chemical]]

~~[[Category:Amphetamine]]~~

[[Category:Stimulant]]

[[Category:Benzofuran]]

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 | ''[[ 5-APB/Summary|Summary sheet:  5-APB]]''
 |}
-'''1-Benzofuran-5-ylpropan-2-amine''' (abbreviated '''5-APB''') is a [[Psychoactive class::entactogen]]ic substance of the [[chemical class::phenethylamine]] and [[chemical class::benzofuran]] classes.
+'''5-(2-aminopropyl)benzofuran''' (abbreviated '''5-APB''') is a synthetic [[Psychoactive class::entactogen]] of the substituted [[chemical class::benzofuran]] class of chemicals, which are known to produce [[euphoria|euphoric]], [[entactogen]]ic, [[stimulant|stimulation]] and mildly [[hallucinogen]]ic effects. These include such [[MDA]]-inspired substances as [[5-APB]], [[6-APB]] and [[5-EAPB]], among others.
 This compound is known for its [[stimulating]] and [[euphoria|euphoric]] effects which has resulted in its rise in popularity as a product which is easily accessible through the use of certain online [[research chemical]] vendors. It has been sold as a [[designer drug]] since 2010.<ref>EMCDDA–Europol 2010 Annual Report on the implementation of Council Decision 2005/387/JHA | http://www.emcdda.europa.eu/publications/implementation-reports/2010</ref>
@@ Line 57: / Line 57: @@
 Anecdotal reports which describe the effects of this compound within our [[experience index]] include:
 {{#ask: [[Category:5-APB]][[Category:Experience]]|format=ul|Columns=1}}
 Additional experience reports can be found here:
 * [https://www.erowid.org/experiences/subs/exp_5APB.shtml Erowid Experience Vaults: 5-APB]
@@ Line 65: / Line 64: @@
 The toxicity and long-term health effects of recreational 5-APB use do not seem to have been studied in any scientific context and the [[Toxicity::exact toxic dosage is unknown]]. This is because 5-APB has very little history of human usage. Anecdotal evidence from people who have tried 5-APB within the community suggest that there do not seem to be any negative health effects attributed to simply trying this drug at low to moderate doses by itself and using it sparingly (but nothing can be completely guaranteed).
-Its agonism for 5-HT2B makes it likely that 5-APB would be cardiotoxic with long-term use, as seen in other 5-HT2B agonists such as [[fenfluramine]] and [[MDMA]].
+-APB's high affinity for the 5-HT2b receptor makes it likely that 5-APB would be cardiotoxic with long-term use, as seen in other 5-HT2B agonists such as [[fenfluramine]] and [[MDMA]].
 It is strongly recommended that one use [[responsible drug use|harm reduction practices]] when using this drug.
@@ Line 92: / Line 91: @@
 *[[Responsible use]]
 *[[Designer drug]]
-*[[Psychedelics]]
 *[[Entactogens]]
 *[[Stimulants]]
-*[[Phenethylamines]]
+*[[5-MAPB]]
 *[[6-APB]]
 *[[MDA]]
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 [[Category:Psychoactive substance]]
 [[Category:Research chemical]]
-[[Category:Amphetamine]]
 [[Category:Stimulant]]
 [[Category:Benzofuran]]