Gabapentinoids: Difference between revisions

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'''Gabapentinoids''' are a class of chemical compounds that are derivatives of [[GABA |gamma-aminobutyric acid]] which block α2δ subunit-containing voltage-dependent calcium [[receptor#Ion_channels |channels]]. While all gabapentinoids block the α2δ channels, they also have unique pharmacological characteristics such as enzyme inhibition.

Gabapentinoids are commonly used for epilepsy, neuropathic pain, and [[restless legs syndrome]]. Gabapentinoids are often [[Sedation |sedating]], have [[Seizure suppression |anticonvulsant]] effects, and [[Anxiety suppression |suppress anxiety]]. Drugs in this class include [[gabapentin]], [[phenibut]] and, [[pregabalin]]. Gabapentinoids can be dangerous when mixed with other [[depressants]] such as [[benzodiazepine |benzodiazepines]], [[alcohol]] and [[opioid |opioids]].

Gabapentinoids are commonly used for epilepsy, neuropathic pain, and [[restless legs syndrome]]. Gabapentinoids are often [[Sedation |sedating]], have [[Seizure suppression |anticonvulsant]] effects, and [[Anxiety suppression |suppress anxiety]]. Drugs in this class include [[gabapentin]], [[F-phenibut]], [[phenibut]] and, [[pregabalin]]. Gabapentinoids can be dangerous when mixed with other [[depressants]] such as [[benzodiazepine |benzodiazepines]], [[alcohol]] and [[opioid |opioids]].

=See also=

*[[Responsible use]]

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 '''Gabapentinoids''' are a class of chemical compounds that are derivatives of [[GABA |gamma-aminobutyric acid]] which block α2δ subunit-containing voltage-dependent calcium [[receptor#Ion_channels |channels]]. While all gabapentinoids block the α2δ channels, they also have unique pharmacological characteristics such as enzyme inhibition.
-Gabapentinoids are commonly used for epilepsy, neuropathic pain, and [[restless legs syndrome]]. Gabapentinoids are often [[Sedation |sedating]], have [[Seizure suppression |anticonvulsant]] effects, and [[Anxiety suppression |suppress anxiety]]. Drugs in this class include [[gabapentin]], [[phenibut]] and, [[pregabalin]]. Gabapentinoids can be dangerous when mixed with other [[depressants]] such as [[benzodiazepine |benzodiazepines]], [[alcohol]] and [[opioid |opioids]].
+Gabapentinoids are commonly used for epilepsy, neuropathic pain, and [[restless legs syndrome]]. Gabapentinoids are often [[Sedation |sedating]], have [[Seizure suppression |anticonvulsant]] effects, and [[Anxiety suppression |suppress anxiety]]. Drugs in this class include [[gabapentin]], [[F-phenibut]], [[phenibut]] and, [[pregabalin]]. Gabapentinoids can be dangerous when mixed with other [[depressants]] such as [[benzodiazepine |benzodiazepines]], [[alcohol]] and [[opioid |opioids]].
 =See also=
 *[[Responsible use]]