Releasing agent: Difference between revisions
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A '''releasing agent''' is a drug that induces the transfer of a [[neurotransmitter]] from the presynaptic [[neurone]] into the synapse, leading to elevated extracellular concentrations of the neurotransmitter, therefore resulting increased neurotransmission. Many drugs use neurotransmitter release to exert their psychological and physiological effects, | A '''releasing agent''' is a drug that induces the transfer of a [[neurotransmitter]] from the presynaptic [[neurone]] into the synapse, leading to elevated extracellular concentrations of the neurotransmitter, therefore resulting increased neurotransmission. Many drugs use neurotransmitter release to exert their psychological and physiological effects, including [[amphetamines]], [[cathinones]], and [[tryptamines]]. Virtually all currently known releasing agents affect the monoamine neurotransmitters [[serotonin]], [[noradrenaline]], and/or [[dopamine]], and as such, they are often referred to more formally as monoamine releasing agents (MRAs). MRAs, like [[agonists]] may be selective for a particular neurotransmitter or non-selective and affect multiple neurotransmitters. | ||
==Mechanism of Action== | ==Mechanism of Action== |