SAM-e: Difference between revisions

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'''S-Adenosyl methionine''' ('''SAMe''' '''Ademethionine''') is a methyl donating compound that circulates in the blood and provides methyl groups to maintain metabolic reactions.<ref>Homocysteine. | https://www.ncbi.nlm.nih.gov/pubmed/10762063</ref> SAMe is an amino acid methionine bound to an ATP molecule; this molecule circulates in the blood naturally and acts as a 'methyl donor'. A methyl group in chemistry is simply a carbon molecule (bound to some hydrogens), and donating a methyl group to other molecules can accelerate or preserve reactions in the body as a form of metabolic 'maintenance'.

'''S-Adenosyl methionine''' ('''SAMe''', '''Ademethionine''') is a methyl donating compound that circulates in the blood and provides methyl groups to maintain metabolic reactions.<ref>Homocysteine. | https://www.ncbi.nlm.nih.gov/pubmed/10762063</ref> SAMe is an amino acid methionine bound to an ATP molecule; this molecule circulates in the blood naturally and acts as a 'methyl donor'. A methyl group in chemistry is simply a carbon molecule (bound to some hydrogens), and donating a methyl group to other molecules can accelerate or preserve reactions in the body as a form of metabolic 'maintenance'.

Sam-e is available over the counter and by prescription in the treatment of depression and osteoarthritis. It is generally distributed in enteric coated tablets, which allows the supplement to pass through the low ph environment of the stomach to the gastrointestinal tract, raising the bioavaliability by 600%. <ref>Bioavailability of S-adenosyl methionine and impact on response in a randomized, double-blind, placebo-controlled trial in major depressive disorder. | http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4156851/</ref>

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-'''S-Adenosyl methionine''' ('''SAMe''' '''Ademethionine''') is a methyl donating compound that circulates in the blood and provides methyl groups to maintain metabolic reactions.<ref>Homocysteine. | https://www.ncbi.nlm.nih.gov/pubmed/10762063</ref> SAMe is an amino acid methionine bound to an ATP molecule; this molecule circulates in the blood naturally and acts as a 'methyl donor'. A methyl group in chemistry is simply a carbon molecule (bound to some hydrogens), and donating a methyl group to other molecules can accelerate or preserve reactions in the body as a form of metabolic 'maintenance'.
+'''S-Adenosyl methionine''' ('''SAMe''', '''Ademethionine''') is a methyl donating compound that circulates in the blood and provides methyl groups to maintain metabolic reactions.<ref>Homocysteine. | https://www.ncbi.nlm.nih.gov/pubmed/10762063</ref> SAMe is an amino acid methionine bound to an ATP molecule; this molecule circulates in the blood naturally and acts as a 'methyl donor'. A methyl group in chemistry is simply a carbon molecule (bound to some hydrogens), and donating a methyl group to other molecules can accelerate or preserve reactions in the body as a form of metabolic 'maintenance'.
 Sam-e is available over the counter and by prescription in the treatment of depression and osteoarthritis. It is generally distributed in enteric coated tablets, which allows the supplement to pass through the low ph environment of the stomach to the gastrointestinal tract, raising the bioavaliability by 600%. <ref>Bioavailability of S-adenosyl methionine and impact on response in a randomized, double-blind, placebo-controlled trial in major depressive disorder. | http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4156851/</ref>