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Releasing agent: Difference between revisions
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==Selectivity== | ==Selectivity== | ||
Releasing agents act to varying extents on the monoamine neurotransmitters. Some will induce the release of all three monoamines; an example of this is [[MDMA]]. Others are more selective as [[methamphetamine]] is a potent releasing agent of dopamine and noradrenaline, but is a weak releaser of serotonin. | Releasing agents act to varying extents on the monoamine neurotransmitters. Some will induce the release of all three monoamines; an example of this is [[MDMA]]. Others are more selective as [[methamphetamine]] is a potent releasing agent of dopamine and noradrenaline, but is a weak releaser of serotonin. A majority of releasing agents are non-selective, but there are currently a limited amount of agents that release serotonin (SRAs) or norephinephrine (NRAs) selectively; no selective dopamine releasing agents are currently known. Many tryptamines, such as [[DMT]], [[DiPT]], and [[psilocin]], are selective serotonin releasing agents in addition to their other pharmacological effects. | ||
==Neurotoxicity== | ==Neurotoxicity== | ||