2M2B: Difference between revisions

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As with any other GABA receptor agonist, repeated use and increasing tolerance will eventually result in a withdrawal syndrome upon abrupt discontinuation resembling alcohol, barbiturate, or [[Benzodiazepine#Discontinuation|benzodiazepine withdrawal]], up to and including delirium tremens ("the shakes"). The chronic use of this compound can be considered [[Addiction potential::moderately addictive with a high potential for abuse]] and is capable of causing psychological dependence among certain users. When addiction has developed, cravings and [[withdrawal effects]] may occur if a person suddenly stops their usage.

Tolerance to many of the effects of ~~2-methyl-2-butanol~~ [[Time to full tolerance::develops with prolonged and repeated use]]. This results in users having to administer increasingly large doses to achieve the same effects. After that, it takes about [[Time to half tolerance::3 - 7 days]] for the tolerance to be reduced to half and [[Time to zero tolerance::1 - 2 weeks]] to be back at baseline (in the absence of further consumption). ~~2-methyl-2-butanol~~ presents cross-tolerance with [[Cross-tolerance::all [[GABA]]genic [[depressants]]]], meaning that after the consumption of ~~2-methyl-2-butanol~~ all [[depressant]]s will have a reduced effect.

Tolerance to many of the effects of 2m2b [[Time to full tolerance::develops with prolonged and repeated use]]. This results in users having to administer increasingly large doses to achieve the same effects. After that, it takes about [[Time to half tolerance::3 - 7 days]] for the tolerance to be reduced to half and [[Time to zero tolerance::1 - 2 weeks]] to be back at baseline (in the absence of further consumption). 2m2b presents cross-tolerance with [[Cross-tolerance::all [[GABA]]genic [[depressants]]]], meaning that after the consumption of 2m2b all [[depressant]]s will have a reduced effect.

===Dangerous interactions===

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*'''[[Depressants]]''' (''[[1,4-Butanediol]], [[alcohol]], [[barbiturates]], [[benzodiazepines]], [[GHB]]/[[GBL]], [[methaqualone]], [[opioids]]'') - This combination can result in dangerous or even fatal levels of [[respiratory depression]]. These substances also potentiate the [[muscle relaxation]], [[sedation]] and [[amnesia]] caused by one another and can lead to unexpected loss of consciousness at high doses. There is also an increased risk of vomiting during unconsciousness and death from the resulting suffocation. If this occurs, users should attempt to fall asleep in the [https://www.youtube.com/watch?v=uCDa-AhrjHo recovery position] or have a friend move them into it.

*'''[[Dissociatives]]''' - This combination can result in an increased risk of vomiting during unconsciousness and death from the resulting suffocation. If this occurs, users should attempt to fall asleep in the [https://www.youtube.com/watch?v=uCDa-AhrjHo recovery position] or have a friend move them into it.

*'''[[Stimulants]]''' - It is dangerous to combine ~~2-methyl-2-butanol~~, a [[depressant]], with [[stimulants]] due to the risk of excessive intoxication. Stimulants decrease the [[sedation|sedative]] effect of ~~2-methyl-2-butanol~~, which is the main factor most people consider when determining their level of intoxication. Once the stimulant wears off, the effects of ~~2-methyl-2-butanol~~ will be significantly increased, leading to intensified [[disinhibition]] as well as [[2-methyl-2-butanol#Subjective effects|other effects]]. If combined, one should strictly limit themselves to only drinking a certain amount of ~~2-methyl-2-butanol~~ per hour.

*'''[[Stimulants]]''' - It is dangerous to combine 2m2b, a [[depressant]], with [[stimulants]] due to the risk of excessive intoxication. Stimulants decrease the [[sedation|sedative]] effect of 2m2b, which is the main factor most people consider when determining their level of intoxication. Once the stimulant wears off, the effects of 2m2b will be significantly increased, leading to intensified [[disinhibition]] as well as [[2-methyl-2-butanol#Subjective effects|other effects]]. If combined, one should strictly limit themselves to only drinking a certain amount of 2m2b per hour.

==Legal issues==

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 As with any other GABA receptor agonist, repeated use and increasing tolerance will eventually result in a withdrawal syndrome upon abrupt discontinuation resembling alcohol, barbiturate, or [[Benzodiazepine#Discontinuation|benzodiazepine withdrawal]], up to and including delirium tremens ("the shakes"). The chronic use of this compound can be considered [[Addiction potential::moderately addictive with a high potential for abuse]] and is capable of causing psychological dependence among certain users. When addiction has developed, cravings and [[withdrawal effects]] may occur if a person suddenly stops their usage.
-Tolerance to many of the effects of 2-methyl-2-butanol [[Time to full tolerance::develops with prolonged and repeated use]]. This results in users having to administer increasingly large doses to achieve the same effects. After that, it takes about [[Time to half tolerance::3 - 7 days]] for the tolerance to be reduced to half and [[Time to zero tolerance::1 - 2 weeks]] to be back at baseline (in the absence of further consumption). 2-methyl-2-butanol presents cross-tolerance with [[Cross-tolerance::all [[GABA]]genic [[depressants]]]], meaning that after the consumption of 2-methyl-2-butanol all [[depressant]]s will have a reduced effect.
+Tolerance to many of the effects of 2m2b [[Time to full tolerance::develops with prolonged and repeated use]]. This results in users having to administer increasingly large doses to achieve the same effects. After that, it takes about [[Time to half tolerance::3 - 7 days]] for the tolerance to be reduced to half and [[Time to zero tolerance::1 - 2 weeks]] to be back at baseline (in the absence of further consumption). 2m2b presents cross-tolerance with [[Cross-tolerance::all [[GABA]]genic [[depressants]]]], meaning that after the consumption of 2m2b all [[depressant]]s will have a reduced effect.
 ===Dangerous interactions===
@@ Line 50: / Line 50: @@
 *'''[[Depressants]]''' (''[[1,4-Butanediol]], [[alcohol]], [[barbiturates]], [[benzodiazepines]], [[GHB]]/[[GBL]], [[methaqualone]], [[opioids]]'') - This combination can result in dangerous or even fatal levels of [[respiratory depression]]. These substances also potentiate the [[muscle relaxation]], [[sedation]] and [[amnesia]] caused by one another and can lead to unexpected loss of consciousness at high doses. There is also an increased risk of vomiting during unconsciousness and death from the resulting suffocation. If this occurs, users should attempt to fall asleep in the [https://www.youtube.com/watch?v=uCDa-AhrjHo recovery position] or have a friend move them into it.
 *'''[[Dissociatives]]''' - This combination can result in an increased risk of vomiting during unconsciousness and death from the resulting suffocation. If this occurs, users should attempt to fall asleep in the [https://www.youtube.com/watch?v=uCDa-AhrjHo recovery position] or have a friend move them into it.
-*'''[[Stimulants]]''' -  It is dangerous to combine 2-methyl-2-butanol, a [[depressant]], with [[stimulants]] due to the risk of excessive intoxication. Stimulants decrease the [[sedation|sedative]] effect of 2-methyl-2-butanol, which is the main factor most people consider when determining their level of intoxication. Once the stimulant wears off, the effects of 2-methyl-2-butanol will be significantly increased, leading to intensified [[disinhibition]] as well as [[2-methyl-2-butanol#Subjective effects|other effects]]. If combined, one should strictly limit themselves to only drinking a certain amount of 2-methyl-2-butanol per hour.
+*'''[[Stimulants]]''' -  It is dangerous to combine 2m2b, a [[depressant]], with [[stimulants]] due to the risk of excessive intoxication. Stimulants decrease the [[sedation|sedative]] effect of 2m2b, which is the main factor most people consider when determining their level of intoxication. Once the stimulant wears off, the effects of 2m2b will be significantly increased, leading to intensified [[disinhibition]] as well as [[2-methyl-2-butanol#Subjective effects|other effects]]. If combined, one should strictly limit themselves to only drinking a certain amount of 2m2b per hour.
 ==Legal issues==