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Serotonin: Difference between revisions
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A serotonin [[Agonist#Agonists|partial agonist]] is a drug that binds to and activates a serotonin receptor, but only has partial efficacy at the receptor relative to a full agonist. | A serotonin [[Agonist#Agonists|partial agonist]] is a drug that binds to and activates a serotonin receptor, but only has partial efficacy at the receptor relative to a full agonist. | ||
Most classical psychedelic drugs are partial agonists of the 5-HT<sub>2A</sub> receptor; among them are [[LSD]], [[psilocin]] and [[mescaline]]. Many antidepressants, | Most classical psychedelic drugs are partial agonists of the 5-HT<sub>2A</sub> receptor; among them are [[LSD]], [[psilocin]] and [[mescaline]]. Many antidepressants, anxiolytics/anti-anxiety drugs, and cluster headache medicines are partial serotonin receptor agonists. | ||
====Releasing agents==== | ====Releasing agents==== | ||
A serotonin [[Releasing Agent|releasing agent]] is a drug that induces the release of serotonin from the presynaptic neuron into the synapse, leading to an increase in the extracellular concentrations of serotonin. | A serotonin [[Releasing Agent|releasing agent]] is a drug that induces the release of serotonin from the presynaptic neuron into the synapse, leading to an increase in the extracellular concentrations of serotonin. | ||