PCP: Difference between revisions
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'''Phencyclidine''', commonly initialized as PCP and known colloquially as Angel Dust, pharmaceutically as Sernyl, and by many other names,[3] is a dissociative drug. PCP was brought to market in the 1950s as an anesthetic pharmaceutical drug but was taken off the market in 1965 due to the high prevalence of dissociative hallucinogenic side effects. Likewise ketamine was discovered by Parke-Davis researchers as a better-tolerated derivative for use as an anesthetic pharmaceutical drug. Since this time a number of synthetic derivatives of PCP have been sold as dissociative drugs for recreational and non-medical use.[4] | '''Phencyclidine''', commonly initialized as '''PCP''' and known colloquially as Angel Dust, pharmaceutically as Sernyl, and by many other names,[3] is a [[dissociative]] drug. PCP was brought to market in the 1950s as an [[Pain relief|anesthetic]] pharmaceutical drug but was taken off the market in 1965 due to the high prevalence of dissociative [[hallucinogenic]] side effects. Likewise [[ketamine]] was discovered by Parke-Davis researchers as a better-tolerated derivative for use as an anesthetic pharmaceutical drug. Since this time a number of synthetic derivatives of PCP have been sold as dissociative drugs for recreational and non-medical use.[4] | ||
In chemical structure, PCP is a member of the arylcyclohexylamine class, and, in pharmacology, it is a member of the family of dissociative anesthetics. PCP works primarily as an NMDA receptor antagonist, where it blocks the activity of the NMDA receptor. As an addictive drug, PCP is associated with compulsive abuse.[1][4][5][6] | In chemical structure, PCP is a member of the [[arylcyclohexylamine]] class, and, in pharmacology, it is a member of the family of dissociative anesthetics. PCP works primarily as an [[NMDA receptor antagonist]], where it blocks the activity of the NMDA receptor. As an addictive drug, PCP is associated with compulsive abuse.[1][4][5][6] | ||
As a recreational drug, PCP may be ingested orally, smoked, insufflated or injected.[7] | As a recreational drug, PCP may be ingested [[orally]], [[smoked]], [[insufflated]] or [[injected]].[7] | ||
==Chemistry== | ==Chemistry== | ||
{{chemistry}} | {{chemistry}} |